# US 11,308,147 B2 · Methods and systems for analyzing and reporting medical images > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,308,147 B2 - Document ID: US11308147B2 - Status: Granted - Kind: B2 - Application number: 14/201,769 - Filed: 2014-03-07 - Published: 2014-09-11 - Granted: 2022-04-19 - Earliest claimed: 2011-09-08 - Assignees: Radlogics, Inc.; Tel HaShomer Medical Research Infrastructure and Services Ltd. - Applicants: Radlogics, Inc.; Tel Hashomer Medical Research, Infrastructure and Services Ltd. - Inventors: Moshe Becker; Robert M. Foley; Eliahu Konen; Arnaldo Mayer - Web page: https://patentgrep.com/patent/US11308147B2 ## CPC - G06F 16/50: of still image data - G16H 15/00: ICT specially adapted for medical reports, e.g. generation or transmission thereof - G16H 30/20: for handling medical images, e.g. DICOM, HL7 or PACS - G16H 50/20: for computer-aided diagnosis, e.g. based on medical expert systems - G06F: ELECTRIC DIGITAL DATA PROCESSING (computer systems based on specific computational models G06N) - G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA ## Abstract A method for providing medical diagnostics comprises providing access to one or more platforms capable of distributing one or more applications for implementing a method. The method comprises retrieving, with the aid of a processor, one or more images from an image database or an imaging device. The one or more images can define a set of images. Next, with the aid of a processor, whether each of the images is of medical interest to a reviewing physician is determined. One or more images can then be provided to a display and analysis system for review by a reviewing physician. The one or more images can be provided with an image that is representative of the set of images. ## Claims ### Claim 1 A method comprising: retrieving, by a computer system, scan data of a predetermined region of a patient's body, the scan data comprising at least one image of the predetermined region; automatically analyzing, using the computer system, the scan data to identify an abnormality relating to the patient's condition using an image processing algorithm; automatically performing, using the computer system, quantitative measurements relating to the abnormality using image analysis, wherein the quantitative measurements are associated with at least one of a distance, a cross-sectional area, and a volume relating to the patient's condition; automatically identifying, using the computer system, a representative image from the scan data based on the identified abnormality and the quantitative measurements relating to the abnormality; automatically generating, using the computer system, an analysis report including at least one of the representative image and the quantitative measurements associated with the representative image; retrieving, using the computer system, a historical analysis report of the predetermined region of the patient's body, wherein the historical analysis report includes at least one of a historical representative image and quantitative measurements associated with the historical representative image; automatically comparing, using the computer system, the quantitative measurements relating to the abnormality in the analysis report with the quantitative measurements relating to the abnormality in the historical analysis report to identify a change in the patient's condition; determining, using a machine learning model, a change in diagnosis associated with the patient based at least in part on the identified change in the patient's condition, the change in diagnosis being indicative of a potential problem in a historical diagnosis or a progression of the patient's condition, wherein the machine learning model was generated by: receiving a plurality of final reports associated with the physician and a corresponding plurality of preliminary reports generated by an initial machine learning model; comparing the plurality of final reports by the physician with the corresponding plurality of preliminary reports to adjust the initial machine learning model to more closely match the plurality of final reports; and further refining the initial machine learning model based at least in part on patient outcome information relating to patient responsiveness to treatment, the treatment being associated with conditions identified in the plurality of preliminary reports generated by the initial machine learning model; and presenting, using the computer system, a preliminary report associated with the change in diagnosis to a physician for review, wherein the preliminary report associated with the change in diagnosis includes at least one of (i) the representative image and historical representative image, (ii) the quantitative measurements relating to the abnormality in the analysis report and the quantitative measurements relating to the abnormality in the historical analysis report, and (iii) the change in diagnosis determined by the machine learning model. ### Claim 2 (depends on 1) The method of claim 1, wherein the abnormality is determined using comparable images or severity range lookup tables based on the patient's condition. ### Claim 3 (depends on 1) The method of claim 1, further comprising retrieving data from one or more additional information source. ### Claim 4 (depends on 3) The method of claim 3, wherein the one or more additional information source includes one or more of the following: news articles, or data from one or more additional patients. ### Claim 5 (depends on 4) The method of claim 4, wherein the additional information is included in the analysis report. ### Claim 6 (depends on 4) The method of claim 4, wherein the additional information is used to analyze the plurality of images associated with the patient. ### Claim 7 (depends on 6) The method of claim 6, further comprising detecting one or more medical conditions of the patient based on using the additional information to analyze the plurality of images associated with the patient. ### Claim 8 (depends on 4) The method of claim 4, wherein the one or more additional patients shares one or more peer group attribute with the patient. ### Claim 9 (depends on 1) The method of claim 1, further comprising providing an alert if parameters associated with the plurality of images fall within one or more boundary parameters, wherein the one or more boundary parameters associated with the plurality of images. ### Claim 10 (depends on 8) The method of claim 8, further comprising retrieving, from a memory location coupled to the processor, data sets associated with the one or more peer group attributes. ### Claim 11 (depends on 1) The method of claim 1, wherein the analysis report comprises diagnostic data. ### Claim 12 (depends on 11) The method of claim 11, wherein the diagnostic data comprises one or more of the following: volume, attributes, measurements, statistics, examples from one or more similar cases of an additional subject, and examples from one or more articles. ### Claim 13 (depends on 11) The method of claim 11, further comprising extracting one or more time-dependent attributes from the diagnostic data. ### Claim 14 (depends on 11) The method of claim 11, further comprising sorting the diagnostic data of the subject according to one or more of the following peer group attributes: age, gender, life style, habits, disease, and stage of disease. ### Claim 15 (depends on 11) The method of claim 11, wherein the diagnostic data comprises two or more of the following: volume, attributes, measurements, statistics, examples from one or more similar cases of an additional subject, and examples from one or more articles. ### Claim 16 (depends on 11) The method of claim 11, wherein the diagnostic data comprises three or more of the following: volume, attributes, measurements, statistics, examples from one or more similar cases of an additional subject, and examples from one or more articles. ### Claim 17 (depends on 1) The method of claim 1, wherein the plurality of images are from a first time point, and wherein the historical analysis report includes time-dependent attributes of one or more images of the patient from a second time point, wherein the second time point precedes the first time point. ### Claim 18 (depends on 17) The method of claim 17, further comprising comparing time-dependent attributes of the set of images of the first time point with historical data and quantifying changes in time-dependent attributes between the first time point and the second time point. ### Claim 19 (depends on 18) The method of claim 18, further comprising generating information on the quantified changes in time-dependent attributes between the first time point and the second time point of at least one image of the set of images, wherein the quantified changes enable tracking a medical progress of said subject. ### Claim 20 (depends on 1) The method of claim 1, further comprising designating an image priority, wherein the image priority is based on comparing each of the plurality of images to the plurality of images. ### Claim 21 (depends on 20) The method of claim 20, wherein the designating an image priority is further based on at least one of additional information and the historical analysis report. ### Claim 22 (depends on 20) The method of claim 20, wherein the image priority includes a designation of high, medium, or low priority. ### Claim 23 (depends on 20) The method of claim 20, wherein the image priority includes a designation of a non-negative integer, wherein higher priority images are assigned a lower numerical value. ### Claim 24 (depends on 22) The method of claim 22, further comprising prioritizing the plurality of images. ### Claim 25 (depends on 23) The method of claim 23, further comprising prioritizing the plurality of images. ### Claim 26 (depends on 1) The method of claim 1, further comprising designating a case priority, wherein the case priority is designated based on the patient's condition. ### Claim 27 (depends on 26) The method of claim 26, wherein the case priority includes a designation of a high, medium, or low priority. ### Claim 28 (depends on 26) The method of claim 26, further comprising prioritizing a plurality of cases. ### Claim 29 (depends on 1) The method of claim 1, wherein the patient's condition comprises pneumothorax, and wherein the quantitative measurements are associated with at least the volume relating to the patient's condition and comprise quantifying a volume of air or a liquid pocket. ### Claim 30 (depends on 1) The method of claim 1, wherein the patient's condition comprises pleural effusion, and wherein the quantitative measurements are associated with at least the volume relating to the patient's condition and comprise quantifying a volume of free liquid and free air in a pleural cavity. ### Claim 31 (depends on 1) The method of claim 1, wherein the patient's condition comprises an aortic dissection, and wherein the quantitative measurements are associated with at least the cross-sectional area relating to the patient's condition and comprise quantifying a cross-sectional dimension of an aorta. ### Claim 32 (depends on 1) The method of claim 1, wherein the patient's condition comprises a fracture, and wherein the quantitative measurements comprise quantifying a dimension of the fracture. ### Claim 33 (depends on 1) The method of claim 1, wherein the patient's condition comprises an intracranial hemorrhage. ### Claim 34 (depends on 1) The method of claim 1, wherein the patient's condition comprises a liver metastasis. ### Claim 35 (depends on 1) The method of claim 1, wherein the patient's condition comprises an aortic aneurysm, and wherein the quantitative measurements comprise quantifying dilation of an aorta. ### Claim 36 (depends on 1) The method of claim 1, further comprising generating an indication of localization of the abnormality in the representative image. ### Claim 37 (depends on 36) The method of claim 36, wherein the analysis report further includes the indication of localization of the abnormality. ### Claim 38 (depends on 37) The method of claim 37, wherein the comparison report further includes the indication of localization of the abnormality. ### Claim 39 (depends on 1) The method of claim 1, further comprising: receiving a final report from the physician after the presenting the preliminary report; comparing the final report with the preliminary report; and further refining the machine learning model based at least in part on the comparison.