# US 11,307,402 B2 · User wearable fluorescence enabled visualization system

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- Number: US 11,307,402 B2
- Document ID: US11307402B2
- Status: Granted
- Kind: B2
- Application number: 17/357,909
- Filed: 2021-06-24
- Published: 2021-10-21
- Granted: 2022-04-19
- Earliest claimed: 2020-04-21
- Assignees: Designs for Vision, Inc.
- Applicants: Designs for Vision, Inc.
- Inventors: Liviu Steier; Richard E. Feinbloom
- Web page: https://patentgrep.com/patent/US11307402B2

## CPC

- G02B 25/02: with means for illuminating object viewed
- G02C 7/088: {Lens systems mounted to spectacles}
- A61B 1/24: for the mouth, i.e. stomatoscopes, e.g. with tongue depressors; Instruments for opening or keeping open the mouth
- A61B 5/0017: {transmitting optical signals}
- A61B 5/0077: {Devices for viewing the surface of the body, e.g. camera, magnifying lens}
- A61B 5/7225: {Details of analogue processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation (input circuits for detecting, measuring, or recording bioelectric or biomagnetic signals A61B5/30; specific diagnostic methods using bioelectric or biomagnetic signals A61B5/316)}
- A61B 90/30: Devices for illuminating a surgical field, the devices having an interrelation with other surgical devices or with a surgical procedure
- A61B 90/35: Supports therefor
- A61B 90/50: Supports for surgical instruments, e.g. articulated arms
- F21V 5/008: {Combination of two or more successive refractors along an optical axis}
- F21V 5/04: of lens shape
- F21V 7/041: {with conical or pyramidal surface}
- F21V 11/08: using diaphragms containing one or more apertures
- F21V 14/02: by movement of light sources {(in vehicle head lamps F21S41/657)}
- F21V 19/02: with provision for adjustment, e.g. for focusing
- F21V 21/084: Head fittings
- F21V 23/003: {the elements being electronics drivers or controllers for operating the light source, e.g. for a LED array}
- F21V 23/04: the elements being switches (safety devices F21V25/00)
- G02B 5/208: {for use with infrared or ultraviolet radiation, e.g. for separating visible light from infrared and/or ultraviolet radiation}
- G02B 5/223: {containing organic substances, e.g. dyes, inks or pigments}
- G02B 7/026: {using retaining rings or springs (G02B7/027 takes precedence)}
- G02B 21/0012: {Surgical microscopes (counterbalanced structures for surgical microscopes G02B7/001)}
- G02B 21/16: adapted for ultraviolet illumination {; Fluorescence microscopes (G02B21/0076 takes precedence)}
- G02B 25/004: {having binocular arrangement}
- G02B 25/008: {comprising two or more lenses (G02B25/004 - G02B25/007 take precedence)}
- G02B 27/0905: {Dividing and/or superposing multiple light beams}
- G02B 27/0972: {Prisms (prisms per se G02B5/04)}
- G02B 27/30: Collimators
- G02C 7/104: {having spectral characteristics for purposes other than sun-protection}
- G02C 11/04: Illuminating means
- A61B 5/0071: {by measuring fluorescence emission}
- A61B 5/0088: {for oral or dental tissue}
- A61B 2090/309: {using white LEDs}
- A61B 2090/502: {Headgear, e.g. helmet, spectacles}
- A61B 2560/0214: of power generation or supply
- F21Y 2113/30: {of visible and non-visible spectrum}
- F21Y 2115/10: Light-emitting diodes [LED]
- G02B 27/017: {Head mounted}
- G02B 2027/0178: {Eyeglass type (eyeglass details G02C)}
- G02C 3/003: {Arrangements for fitting and securing to the head in the position of use}
- G02C 7/086: {Auxiliary lenses located directly on a main spectacle lens or in the immediate vicinity of main spectacles}
- G02B: OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02C: SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES (trial frames for testing the eyes A61B3/04; goggles or eyeshields not having the same features as spectacles A61F9/00)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- F21V: FUNCTIONAL FEATURES OR DETAILS OF LIGHTING DEVICES OR SYSTEMS THEREOF; STRUCTURAL COMBINATIONS OF LIGHTING DEVICES WITH OTHER ARTICLES, NOT OTHERWISE PROVIDED FOR
- F21Y: INDEXING SCHEME ASSOCIATED WITH SUBCLASSES F21K, F21L, F21S and F21V, RELATING TO THE FORM OR THE KIND OF THE LIGHT SOURCES OR OF THE COLOUR OF THE LIGHT EMITTED

## Abstract

A user-wearable fluorescence based visualization system comprising a multi-light lamp assembly that provides for the selected output of light using multiple light emitting sources, wherein the outputted light may be tailored to generate response wavelength by the interaction of the emitted light and a tissue illuminated by the emitted light, through the process of fluorescence, and a viewing system that allows a practitioner view the fluorescent light generated by the tissue, and distinguish between healthy and diseased tissues.

## Claims

### Claim 1

A user wearable device comprising:
a light assembly configured to generate a light, said light assembly comprising:
a plurality of lighting elements, said plurality of lighting elements configured to:
emit a light, toward an object, said emitted light being at least one of: a substantially white light and at least one colored light;
an electrical circuitry comprising:
a switch control configured to:
generate an indication of a change in state of a remote switch, said switch control comprising one of;
a touch control, a touch less control and a wireless control; and
a switch, said switch configured to:
receive said indication; and
control, in response to said received indication, an application of a voltage to at least one of said plurality of lighting elements; and
an eyewear, said eyewear configured to:
view a second light, wherein said second light comprises at least one of: a reflection of said emitted light and a light generated by an interaction of said emitted light with said object, said eyewear comprising:
a first lens; and
a second lens, each of said first lens and said second lens comprising a filtering system, wherein said filtering system is configured to:
attenuate light wavelengths within said second light below a known wavelength value; and
allow passage of light wavelengths within said second light above said known wavelength value, wherein a wavelength of said light generated by said interaction of said emitted light with said object is greater than said known value.

### Claim 2 (depends on 1)

The user wearable device as recited in claim 1, wherein each of said first lens and said second lens comprises:
a magnification device, said magnification device configured to:
magnify said second light by a known level of magnification, said magnification device comprising:
at least one filter associated with said magnification device, said at least one filter associated with said magnification device configured to:
attenuate said light wavelengths within said second light below said known wavelength value; and
allow passage of said light wavelengths within said second light above said known wavelength value.

### Claim 3 (depends on 1)

The user wearable device as recited in claim 1, wherein said object comprises:
an enhancement agent, said enhancement agent comprises one of:
an injectable administered agent, an orally administered agent, a systematic agent and an agent applied to said object.

### Claim 4 (depends on 1)

The user wearable device as recited in claim 1, wherein said plurality of lighting elements are arranged concentrically about a central axis extending from said light assembly and oriented to project a light generated by a corresponding one of said plurality of lighting elements to a common point along said central axis, wherein selected one of said plurality of lighting elements comprising:
a transmission filter, said transmission filter configured to limit a light wavelength range of light generated by a corresponding one of said lighting elements.

### Claim 5 (depends on 1)

The user wearable device as recited in claim 1, wherein at least one colored light is transmitted at different power levels.

### Claim 6 (depends on 1)

The user wearable device as recited in claim 1, comprising:
a battery configured to:
provide said voltage to said electronic circuit, said battery being one of: attached to said light assembly and remotely positioned from said light assembly.

### Claim 7 (depends on 1)

The user wearable device as recited in claim 1, wherein said at least one colored light comprises:
a light in a lower range of a blue light wavelength range; and
a light in an upper range of said blue light wavelength range.

### Claim 8

A user wearable device comprising:
an eyewear comprising:
a first lens; and
a second lens, each of said first lens and said second lens comprising:
a filtering system; and
a light assembly attached to said eyewear, said light assembly comprising:
a plurality of lighting elements arranged linearly along a line substantially perpendicular to a central axis extending from said light assembly and oriented to project a light generated by a corresponding one of said a lighting elements to a common point along said central axis, wherein selected one of said plurality of lighting elements comprise:
a transmission filter, said transmission filter configured to limit a light wavelength range of light projected by a corresponding one of said lighting elements, said projected light being at least one of: a substantially white light and at least one colored light, wherein said filter system is configured to:
attenuate light wavelengths within a second light below a known wavelength value; and
allow passage of light wavelengths within said second light above said known wavelength value, said second light comprising a reflection of said projected light and a light generated by an interaction of said projected light with an object.

### Claim 9 (depends on 8)

The user wearable device as recited in claim 8, wherein said at least one colored light comprises:
a light in a lower range of a blue light wavelength range; and
a light in an upper range of said blue light wavelength range.

### Claim 10 (depends on 8)

The user wearable device as recited in claim 8, wherein said at least one colored light is transmitted at different power levels.

### Claim 11 (depends on 8)

The user wearable device as recited in claim 8, comprising:
a source of electrical energy, said source configured to generate a voltage; and
an electrical circuitry comprising:
a switch control configured to:
generate an indication of a change in state of a remote switch, said switch control comprising one of:
a touch control, a touchless control and a wireless control; and
a switch, said switch configured to:
receive said indication; and
control, in response to said received indication, an application of said voltage to at least one of said plurality of lighting elements.

### Claim 12 (depends on 9)

The user wearable device as recited in claim 9, wherein said known wavelength is greater than said light in said lower range of a blue light wavelength range; and
less than said light in said upper range of said blue light wavelength range.

### Claim 13

A user wearable device comprising:
an eyewear comprising:
a first lens; and
a second lens, each of said first lens and said second lens comprising:
a filter system; and
a light assembly said light assembly comprising:
at least one lighting element comprising:
a plurality of lighting sources arranged along an inner circumference of a corresponding one of said at least one lighting element, said plurality of lighting sources configured to:
generate one of: a substantially white light and at least one colored light a light, and
a transmission filter, said transmission filter configured to limit a light wavelength range of light generated by said plurality of light sources within a corresponding one of said at least one lighting element; and
a light director configured to redirect said generated light from said plurality of lighting sources toward said transmission filter, wherein said filter system is configured to:
attenuate light wavelengths within a second light below a known wavelength value; and
allow passage of light wavelengths within said second light above said known wavelength value, wherein said second light comprises wavelengths of said generated light and a light generated by an interaction of said generated light with an object.

### Claim 14 (depends on 13)

The user wearable device as recited in claim 13, wherein said at least one colored light comprises:
a light in a lower range of a blue light wavelength range; and
a light in an upper range of said blue light wavelength range.

### Claim 15 (depends on 14)

The user wearable device as recited in claim 14, wherein said known wavelength value is greater than said light in said lower range of a blue light wavelength range; and
less than said light in said upper range of said blue light wavelength range.

### Claim 16 (depends on 13)

The user wearable device as recited in claim 13, wherein said at least one colored light is transmitted at different power levels.

### Claim 17 (depends on 13)

The user wearable device as recited in claim 13, comprising:
a source of electrical energy, said source configured to generate a voltage; and
an electrical circuitry comprising:
a switch control configured to:
generate an indication of a change in state of a remote switch, said switch control comprising one of:
a touch control, a touchless control and a wireless control; and
a switch, said switch configured to:
receive said indication; and
control, in response to said received indication, an application of said voltage to at least one of said plurality of lighting elements.