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US 11,305,275 B2Granted
Bodily fluid sample collection and transport
AssigneeLabrador Diagnostics LLC
InventorsElizabeth A. Holmes, Clarissa Lui, Michael Chen, Daniel Young
Life of this patent
Estimating the term…
Abstract
Bodily fluid sample collection systems, devices, and method are provided. The sample is collected at a first location and subjected to a first sample processing step. The sample may be shipped to a second location and subjected to a second sample processing step that does not introduce contaminants into a plasma portion of the sample formed from the first processing step. The sample may also be mixed with other material(s) in the collection device.
Claims7
A method comprising:
- receiving, in a channel, a bodily fluid sample provided by a subject;
- mixing the bodily fluid sample with an anticoagulant to generate a mixed bodily fluid sample;
- and
- collecting, in a vessel in fluid communication with the channel, the mixed bodily fluid sample,
- wherein the anticoagulant comprises EDTA, and wherein the mixed bodily fluid sample comprises a bulk concentration of EDTA no less than about 2.5 milligrams per milliliter and no greater than about 10 milligrams per milliliter, wherein a concentration of the anticoagulant coating varies along a length of the channel according to a gradient.
2 more elements
A method comprising:
- receiving, in a channel, a bodily fluid sample provided by a subject;
- mixing the bodily fluid sample with an anticoagulant to generate a mixed bodily fluid sample;
- and
- collecting, in a vessel in fluid communication with the channel, the mixed bodily fluid sample,
- wherein the anticoagulant comprises heparin, and wherein the mixed bodily fluid sample comprises a bulk concentration of heparin no less than about 20 units per milliliter and no greater than about 150 units per milliliter, wherein a thickness of the anticoagulant coating varies along a length of the channel according to a gradient.
2 more elements
A method comprising:
- receiving, in a channel, a bodily fluid sample provided by a subject;
- mixing the bodily fluid sample with an anticoagulant to generate a mixed bodily fluid sample;
- and
- collecting, in a vessel in fluid communication with the channel, the mixed bodily fluid sample,
- wherein the anticoagulant comprises EDTA, and wherein the mixed bodily fluid sample comprises a bulk concentration of EDTA no less than about 2.5 milligrams per milliliter and no greater than about 10 milligrams per milliliter, wherein a concentration of the anticoagulant coating varies along a length of the channel according to a gradient;
- wherein mixing the bodily fluid sample with the anticoagulant comprises mixing the bodily fluid sample with the anticoagulant with a shear rate no greater than about 1,000 reciprocal seconds.
3 more elements
Dependencies are inferred from the claim text.