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US 11,305,039 B2Granted
Polymeric vascular grafts which induce neovascularization with mild to minimal inflammation and promotion of fibrovascular tissue
AssigneesVanderbilt University, Venostent, Inc.
InventorTimothy C. Boire
Life of this patent
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Abstract
The present invention relates generally to shape memory polymer devices that are porous. The porosity of the device may generate advantageous neovascularization, decrease inflammation, and decrease fibrosis. The device may include a surface having a pore size of 500-750 microns and a pore spacing of 220-250 microns.
Claims20
An implantable tissue supporting device comprising:
- a biodegradable polymeric scaffold capable of surrounding a tissue, the biodegradable polymeric scaffold includes at least one polymer, the at least one polymer comprising at least one monomer that is crosslinkable, wherein the biodegradable polymeric scaffold is configured to have a melting temperature and be moldable from a first shape to a second shape by an external force when the melting temperature is met or exceeded, wherein the device is mechanically compliant at from about 20 to about 50° C., and wherein the biodegradable polymeric scaffold has a pore size of about 500-750 μm and a pore spacing of about 220 μm to about 250 μm.
Dependencies are inferred from the claim text.