# US 11,304,886 B2 · N-acyl sarcosines as antimicrobials for preservation of home and personal care products

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- Number: US 11,304,886 B2
- Document ID: US11304886B2
- Status: Granted
- Kind: B2
- Application number: 15/999,810
- Filed: 2017-02-13
- Published: 2021-06-03
- Granted: 2022-04-19
- Earliest claimed: 2016-02-20
- Assignees: Galaxy Surfactants Ltd.
- Applicants: Galaxy Surfactants Ltd.
- Inventors: Bhagyesh Jagannath Sawant; Devyani Ashok Mali; Arpit Wankhade; Nirmal Koshti
- Web page: https://patentgrep.com/patent/US11304886B2

## CPC

- A01N 37/46: N-acyl derivatives
- A61K 8/44: Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K 8/042: {Gels}
- A61K 8/062: {Oil-in-water emulsions}
- A61Q 19/00: Preparations for care of the skin
- A61Q 19/10: Washing or bathing preparations
- C11D 1/10: Amino carboxylic acids; Imino carboxylic acids; Fatty acid condensates thereof
- C11D 3/48: Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
- A61K 2800/10: General cosmetic use
- A61K 2800/524: Preservatives
- A61K 2800/74: Biological properties of particular ingredients
- A01N: PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF (preservation of food or foodstuff A23); BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES (preparations for medical, dental or toiletry purposes which kill or prevent the growth or proliferation of unwanted organisms A61K); PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- C11D: DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL

## Abstract

N-Acyl sarcosines of Formula I, wherein, R═C7 alkyl and C10 alkenyl group with terminal double bond, are described as new antimicrobial preservatives for home and personal care products. Lipidated sarcosines of this patent application preserve creams, lotions, emulsions, solutions or suspensions types of formulations of personal care industry. These are used in: leave-on ̆ (cold cream, sunscreen) as well as: rinse-off ̆ (facewash, body wash, shampoo) formulations either alone or in combination with other antimicrobials.

## Claims

### Claim 1

A composition comprising:
at least 0.5% w/w of a liquid N-acyl sarcosine of Formula I:
at least 0.5% w/w phenoxy ethanol; and
one or more ingredients selected from the group consisting of surfactants, vegetable oils, petrolatum, mineral oils moisturizers, humectants, rheology modifiers, silicones, cationic conditioners, pearly waxes, emollients, skin actives and hair actives, UV absorbers, film formers, vitamins, solvents, water, and antimicrobials;
wherein the liquid N-acyl sarcosine comprises a mixture containing N-capryloyl sarcosine and N-undecylenoyl sarcosine in a ratio of 1:1.
