# US 11,304,855 B2 · Buffered adhesive compositions for skin-adhering medical products > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,304,855 B2 - Document ID: US11304855B2 - Status: Granted - Kind: B2 - Application number: 16/703,073 - Filed: 2019-12-04 - Published: 2020-04-02 - Granted: 2022-04-19 - Earliest claimed: 2012-02-29 - Assignees: Hollister Incorporated - Applicants: Hollister Incorporated - Inventors: Jan Wohlgemuth; Mette Maack; Carsten Rikhof; Peter Skov; Kristoffer Nielsen; Per Ladefoged; Kenneth Nielsen; Michael Taylor; Richard Murahata - Web page: https://patentgrep.com/patent/US11304855B2 ## CPC - A61F 13/0253: {characterized by the adhesive material} - A61F 5/443: having {adhesive seals for securing to the body, e.g. of} hydrocolloid type seals, e.g. gels, starches or karaya gums - A61F 13/0203: with fluid retention members - A61L 15/585: {Mixtures of macromolecular compounds} - A61L 15/60: Liquid-swellable gel-forming materials, e.g. super-absorbents - A61L 24/0031: {Hydrogels or hydrocolloids} - A61L 24/043: {Mixtures of macromolecular materials} - A61L 26/0052: {Mixtures of macromolecular compounds} - A61L 26/008: {Hydrogels or hydrocolloids} - C08L 23/18: Homopolymers or copolymers of hydrocarbons having four or more carbon atoms - C08L 33/02: Homopolymers or copolymers of acids; Metal or ammonium salts thereof - C08L 53/02: of vinyl-aromatic monomers and conjugated dienes - C09J 123/20: having four to nine carbon atoms - C09J 123/22: Copolymers of isobutene; Butyl rubber {; Homo- or copolymers of other iso-olefines} - C09J 133/02: Homopolymers or copolymers of acids; Metal or ammonium salts thereof - C08L 2205/16: Fibres; Fibrils - C08L 2205/22: Mixtures comprising a continuous polymer matrix in which are dispersed crosslinked particles of another polymer - A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C) - A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K) - C08L: COMPOSITIONS OF MACROMOLECULAR COMPOUNDS (compositions based on polymerisable monomers C08F, C08G; artificial filaments or fibres D01F; textile treating compositions D06) - C09J: ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES (preparation of glue or gelatine C09H) ## Abstract Provided are buffered adhesive compositions comprising a high molecular weight non-neutralized polymeric acid and a high molecular weight partially neutralized polymeric acid and products such as wound dressings and ostomy skin barriers incorporating the compositions. ## Claims ### Claim 1 An ostomy skin barrier comprising: a first pressure sensitive adhesive; a second adhesive, the second adhesive including PIB, SIS copolymer, pectin and CMC, the second adhesive being a pressure sensitive adhesive; and a buffer composition including a non-neutralized polyacrylic acid and a partially neutralized polyacrylic acid. ### Claim 2 (depends on 1) The ostomy skin barrier of claim 1, further comprising: a first barrier surface containing the first adhesive; and a second barrier surface containing the second adhesive. ### Claim 3 (depends on 2) The ostomy skin barrier of claim 2, wherein the first barrier surface is an inner layer formed from the first adhesive and the second barrier surface is a backing layer formed from the second adhesive, wherein the backing layer extends over and beyond the inner layer to form an edge portion of the barrier. ### Claim 4 (depends on 2) The ostomy skin barrier of claim 2, wherein the first barrier surface is configured to contact a peristomal area that is immediately adjacent to a wearer's stoma. ### Claim 5 (depends on 1) The ostomy skin barrier of claim 1, wherein the second adhesive has a lower absorptive capacity than the first adhesive. ### Claim 6 An ostomy skin barrier comprising: a first adhesive; a second adhesive, the second adhesive including a hydrocolloid, the second adhesive being a pressure sensitive adhesive; a buffer composition; and wherein the buffer composition includes 20 wt. % of cross linked polyacrylic acid and 15 wt. % of cross linked partially neutralized polyacrylic acid. ### Claim 7 An ostomy skin barrier comprising: a first adhesive; a second adhesive, the second adhesive including a hydrocolloid, a buffer composition, the second adhesive being a pressure sensitive adhesive; and wherein the second adhesive includes 55.5 wt. % polyisobutylene, 14.5 wt. % of styrene-isoprene-styrene copolymer, 5 wt. % of polyethylene fibers, 8.3 wt. % of pectin, and 16.7 wt. % of CMC. ### Claim 8 An ostomy skin barrier comprising: a first adhesive; a second adhesive, the second adhesive including a hydrocolloid, the second adhesive being a pressure sensitive adhesive; a buffer composition; and wherein the buffer composition includes 20 wt. % of cross linked polyacrylic acid and 15 wt. % of cross linked partially neutralized polyacrylic acid, and the second adhesive includes 55.5 wt. % polyisobutylene, 14.5 wt. % of styrene-isoprene-styrene copolymer, 5 wt. % of polyethylene fibers, 8.3 wt. % of pectin, and 16.7 wt. % of CMC. ### Claim 9 A wound dressing comprising: a flexible outer layer; a first adhesive; a second adhesive including a hydrocolloid, the second adhesive being a pressure sensitive adhesive; a buffer composition; and wherein the first and second adhesives are applied to a side of the flexible outer layer; and wherein the buffer composition includes a non-neutralized polyacrylic acid and a partially neutralized polyacrylic acid. ### Claim 10 (depends on 9) The wound dressing of claim 9, wherein the second adhesive has a lower absorptive capacity than the first adhesive.