# US 11,299,514 B2 · Antimicrobial peptide AS-hepc3(48-56) of Acanthopagrus schlegelii and method thereof

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- Number: US 11,299,514 B2
- Document ID: US11299514B2
- Status: Granted
- Kind: B2
- Application number: 17/373,042
- Filed: 2021-07-12
- Published: 2021-11-04
- Granted: 2022-04-12
- Earliest claimed: 2019-10-09
- Assignees: Xiamen University
- Applicants: Xiamen University
- Inventors: Kejian Wang; Depeng Zhu; Hui Peng; Fangyi Chen; Huiyun Chen
- Web page: https://patentgrep.com/patent/US11299514B2

## CPC

- C07K 7/06: having 5 to 11 amino acids
- A61P 31/04: Antibacterial agents
- C07K 14/461: {from fish}
- A61K 38/00: Medicinal preparations containing peptides (peptides containing beta-lactam rings A61K31/00; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, A61K31/00; ergot alkaloids of the cyclic peptide type A61K31/48; containing macromolecular compounds having statistically distributed amino acid units A61K31/74; medicinal preparations containing antigens or antibodies A61K39/00; medicinal preparations characterised by the non-active ingredients, e.g. peptides as drug carriers, A61K47/00)
- Y02A 50/30: Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
- C07K: PEPTIDES (peptides in foodstuffs A23; obtaining protein compositions for foodstuffs, working-up proteins for foodstuffs A23J; preparations for medicinal purposes A61K; peptides containing beta-lactam rings C07D; cyclic dipeptides not having in their molecule any other peptide link than those which form their ring, e.g. piperazine-2,5-diones, C07D; ergot alkaloids of the cyclic peptide type C07D519/02; macromolecular compounds having statistically distributed amino acid units in their molecules, i.e. when the preparation does not provide for a specific; but for a random sequence of the amino acid units, homopolyamides and block copolyamides derived from amino acids C08G69/00; macromolecular products derived from proteins C08H1/00; preparation of glue or gelatine C09H; single cell proteins, enzymes C12N; genetic engineering processes for obtaining peptides C12N15/00; compositions for measuring or testing processes involving enzymes C12Q; investigation or analysis of biological material G01N33/00)
- A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- Y02A: TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE

## Abstract

The present disclosure discloses an antimicrobial peptide AS-hepc3(48-56) of Acanthopagrus schlegelii and method thereof. A molecular formula of the antimicrobial peptide AS-hepc3(48-56) is C48H86N24O10S3, and an amino acid sequence of the antimicrobial peptide AS-hepc3(48-56) is SEQ ID NO: 01.

## Claims

### Claim 1

An antimicrobial peptide consisting of SEQ ID NO: 1.

### Claim 2 (depends on 1)

The antimicrobial peptide according to claim 1, wherein a molecular weight of the antimicrobial peptide is 1255.567 Daltons.

### Claim 3 (depends on 1)

A method for preparing an antimicrobial drug, comprising:
dissolving the antimicrobial peptide according to claim 1 in a solution.

### Claim 4

An antimicrobial drug, comprising:
an antimicrobial peptide consisting of SEQ ID NO: 1.

### Claim 5 (depends on 2)

A method for preparing an antimicrobial drug, comprising:
dissolving the antimicrobial peptide according to claim 2 in a solution.