# US 11,298,542 B2 · Method and system for suicide risk assessment and intervention

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- Number: US 11,298,542 B2
- Document ID: US11298542B2
- Status: Granted
- Kind: B2
- Application number: 16/571,286
- Filed: 2019-09-16
- Published: 2021-03-18
- Granted: 2022-04-12
- Earliest claimed: 2019-09-16
- Assignees: AddBrain Inc
- Applicants: Dorian Aur
- Inventors: Dorian Aur
- Web page: https://patentgrep.com/patent/US11298542B2

## CPC

- A61N 1/36096: {Mood disorders, e.g. depression, anxiety or panic disorder}
- A61B 5/0006: {ECG or EEG signals}
- A61B 5/165: {Evaluating the state of mind, e.g. depression, anxiety}
- A61B 5/372: Analysis of electroencephalograms
- A61B 5/4848: {Monitoring or testing the effects of treatment, e.g. of medication}
- A61B 6/501: {for diagnosis of the head, e.g. neuroimaging or craniography}
- A61N 1/36025: {for treating a mental or cerebral condition}
- G16H 20/10: relating to drugs or medications, e.g. for ensuring correct administration to patients
- G16H 20/30: relating to physical therapies or activities, e.g. physiotherapy, acupressure or exercising
- G16H 20/70: relating to mental therapies, e.g. psychological therapy or autogenous training
- G16H 50/20: for computer-aided diagnosis, e.g. based on medical expert systems
- G16H 50/30: for calculating health indices; for individual health risk assessment
- G16H 70/40: relating to drugs, e.g. their side effects or intended usage
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G16H: HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA

## Abstract

A brain mapping system and methods that allow to predict and monitor the risk of suicide and provide personalized therapy. The brain mapping system and methods detect if brain dysfunctions (injuries) are located in suicidal hubs that trigger increased suicidal ideation and high risk of suicide. The brain mapping technology is suited for different technologies and allows to monitor the effects of therapy, provide precise therapy to decrease the risk of suicide.

## Claims

### Claim 1

A brain mapping method for predicting and monitoring the risk of suicide comprising:
a. using electroencephalographic (EEG) signals and a computing system (device) to estimated network measures and topographically display a network fragmentation map of the whole brain to reveal a network dysfunction located inside a suicidal hub;
b. detecting of proximity and finding when the position of said network dysfunction is in the proximity of said suicidal hubs which triggers suicidal ideation and increases the risk of suicide;
c. predicting and monitoring of high risk of suicide when the network dysfunctions is located in the proximity or inside of said suicidal hubs that are further comprising the left frontal region at electrode F7 or left temporal region at T7 site or in the right occipital region at electrode O2 or frontocentral region at electrode FCz or fronto-polar regions at electrode FP2 or left sensorimotor cortex at electrode FC3 and right centroparietal region at CP4 site;
d. providing a precise individualized therapy using a non-invasive or invasive stimulation or drugs to target the location of said network dysfunctions located in the proximity or inside of said suicidal hubs to diminish or remove the network dysfunction and reduce the risk of suicide.

### Claim 2 (depends on 1)

The method as set forth in claim 1, determines the locations of the network dysfunctions using the network fragmentation map through visual inspection or automatically by the computing system detecting the color scale of said network fragmentation map.

### Claim 3 (depends on 1)

The method as set forth in claim 1, that topographically maps estimated network complexity measures wherein said network fragmentation brain map is plotted as said by the computing system.

### Claim 4 (depends on 1)

The method as set forth in claim 1, wherein said the presence of network dysfunctions (injuries)-in two or more locations within or in a proximity of said suicidal hubs has a cumulative effect and can increase or decrease the risk of suicide.

### Claim 5 (depends on 1)

The method as set forth in claim 1, wherein said the removal of dysfunctional (injured) networks located within of said suicidal hubs or in their proximity by further therapy is required to reduce suicidal ideation and the risk of suicide and antisocial behavior.

### Claim 6 (depends on 1)

The method as set forth in claim 1, wherein said non-invasive stimulation is set to target dysfunctional (injured) brain regions with as said network dysfunctions while the other electrodes can be placed far from dysfunctional regions located on shoulder or right supraorbital ridge or spinal cord.

### Claim 7 (depends on 1)

The method and system as set forth in claim 1, predicts and monitors the effects of different therapies (drug administration) that could potentially trigger suicide or antisocial behavior by expanding or shifting the location of network dysfunctions (injuries) in the proximity of said suicidal hubs once therapy has started and after therapy.

### Claim 8 (depends on 1)

The method as set forth in claim 1, further defines the proximity as less than minimum half distance between adjacent EEG electrodes of a 32 channel EEG system using 10-20 EEG placement.