# US 11,298,512 B2 · Devices and methods for treating acute kidney injury

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- Number: US 11,298,512 B2
- Document ID: US11298512B2
- Status: Granted
- Kind: B2
- Application number: 16/385,222
- Filed: 2019-04-16
- Published: 2020-03-12
- Granted: 2022-04-12
- Earliest claimed: 2013-12-27
- Assignees: RenalPro Medical, Inc.
- Applicants: RenalPro Medical, Inc.
- Inventors: Tsung-Chun Lee; Wen-Pin Shih
- Web page: https://patentgrep.com/patent/US11298512B2

## CPC

- A61M 25/1011: {Multiple balloon catheters}
- A61B 17/12036: {partial occlusion}
- A61B 17/1204: {temporary occlusion}
- A61B 17/12109: {in a blood vessel}
- A61B 17/12136: {Balloons}
- A61M 5/007: {for contrast media}
- A61M 60/13: by means of a catheter allowing explantation, e.g. catheter pumps temporarily introduced via the vascular system
- A61M 60/295: Balloon pumps for circulatory assistance
- A61M 60/33: of kidneys
- A61M 60/497: for balloon pumps for circulatory assistance
- A61M 60/531: using blood pressure data, e.g. from blood pressure sensors
- A61M 60/867: using position detection during deployment, e.g. for blood pumps mounted on and driven through a catheter
- A61B 2090/063: {for measuring volume}
- A61B 2090/064: {for measuring force, pressure or mechanical tension}
- A61M 60/148: in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
- A61M 60/414: transmitted by a rotating cable, e.g. for blood pumps mounted on a catheter
- A61M 2025/0002: {with a pressure sensor at the distal end}
- A61M 2025/0073: {Tip designed for influencing the flow or the flow velocity of the fluid, e.g. inserts for twisted or vortex flow}
- A61M 2025/1052: {for temporarily occluding a vessel for isolating a sector}
- A61M 2025/1079: {having radio-opaque markers in the region of the balloon}
- A61M 2025/1095: {with perfusion means for enabling blood circulation while the balloon is in an inflated state or in a deflated state, e.g. permanent by-pass within catheter shaft}
- A61M 2205/32: with radio-opaque indicia
- A61M 2205/3327: Measuring
- A61M 2210/1082: Kidney
- A61M 2210/12: Blood circulatory system
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)

## Abstract

A catheter devices/systems and methods therefrom are described herein for treating acute kidney injury, especially the contrast-induced acute kidney injury wherein the devices prevent the contrast dyes from entering into kidney and/or facilitate blood flow of kidney by said catheter system.

## Claims

### Claim 1

A device for preventing acute kidney injury from contrast agent introduced into vasculature of a subject, the device comprising:
a catheter shaft having a first lateral side and a second lateral side;
a first expandable member disposed on and extending only along a first lateral side of the catheter shaft; and
a second expandable member disposed on and extending only along a second lateral side of the catheter shaft,
wherein the first and second expandable members have an expanded configuration in which when advanced into an abdominal aorta and positioned adjacent renal artery ostia of the subject are sized to occlude the renal artery ostia while allowing blood flow over the catheter shaft.

### Claim 2 (depends on 1)

The device of claim 1, wherein at least a portion of one or more of the catheter shaft, first expandable member, or second expandable member is radio-opaque.

### Claim 3 (depends on 1)

The device of claim 1, wherein the first expandable member comprises a first inflatable balloon and the second expandable member comprises a second inflatable balloon.

### Claim 4 (depends on 3)

The device of claim 3, wherein the catheter shaft comprises an inflation lumen to provide inflation fluid to expand the first and second inflatable balloons.

### Claim 5 (depends on 4)

The device of claim 4, wherein the inflation lumen is in fluid connection with one or more of the first or second inflatable balloons through at least one connection tube.

### Claim 6 (depends on 1)

The device of claim 1, further comprising a pressure sensor coupled to one or more of first or second expandable members.

### Claim 7 (depends on 1)

The device of claim 1, further comprising a size-measuring sensor coupled to one or more of first or second expandable members.

### Claim 8 (depends on 1)

The device of claim 1, wherein the catheter shaft comprises an infusion port for introducing a fluid into the abdominal aorta.

### Claim 9 (depends on 8)

The device of claim 8 wherein the fluid is one of a contrast agent, a saline, or a medication.

### Claim 10 (depends on 1)

The device of claim 1 further comprising a pressure senor coupled to the shaft adjacent to the first expandable member or the second expandable member.

### Claim 11 (depends on 6)

The device of claim 6 further comprising a control box coupled to a proximal end of the catheter and to the pressure sensor, the control box configured to exhibit data from the pressure sensor.

### Claim 12 (depends on 10)

The device of claim 10 further comprising a control box coupled to a proximal end of the catheter and to the pressure sensor, the control box configured to exhibit data from the pressure sensor.

### Claim 13 (depends on 1)

The device of claim 1 wherein the first expandable member comprises a first inflatable balloon and the second expandable member comprises a second inflatable balloon further comprising: a control box coupled to a proximal end of the catheter configured to control the inflation/deflation of the first inflatable balloon and the second inflatable balloon.

### Claim 14 (depends on 1)

The device of claim 1 wherein the first expandable member disposed on and extending only along a first lateral side of the catheter shaft is a first balloon and the second expandable member disposed on and extending only along a second lateral side of the catheter shaft is a second balloon, further comprising at least one connection tube extending from the first lateral side of the catheter connecting the first balloon to the first lateral side of the catheter and at least one connection tube extending from the second lateral side of the catheter connecting the second balloon to the second lateral side of the catheter.
