# US 11,298,476 B2 · Vibrating blister > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,298,476 B2 - Document ID: US11298476B2 - Status: Granted - Kind: B2 - Application number: 15/967,787 - Filed: 2018-05-01 - Published: 2018-08-30 - Granted: 2022-04-12 - Earliest claimed: 2012-09-26 - Assignees: Boehringer Ingelheim International GmbH - Applicants: Boehringer Ingelheim International GmbH - Inventors: Andree Jung; Stephen Terence Dunne - Web page: https://patentgrep.com/patent/US11298476B2 ## CPC - A61M 15/00: Inhalators {(drug delivery in endotracheal tubes A61M16/04)} - A61M 15/0005: {with means for agitating the medicament} - A61M 15/0028: {using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up} - A61M 15/003: {using capsules, e.g. to be perforated or broken-up} - A61M 15/0035: {Piercing means} - A61M 15/0041: {with movable piercing or cutting means} - A61M 15/0043: {Non-destructive separation of the package, e.g. peeling} - A61M 15/0051: {the dosages being arranged on a tape, e.g. strips} - A61M 15/0045: {using multiple prepacked dosages on a same carrier, e.g. blisters} - A61M 15/06: Inhaling appliances shaped like cigars, cigarettes or pipes - A61M 2202/064: Powder - F04C 2270/041: Controlled or regulated - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} - F04C: ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS (engines F03C); ROTARY-PISTON, OR OSCILLATING-PISTON, POSITIVE-DISPLACEMENT PUMPS ## Abstract Disclosed is an inhaler and a method for using the inhaler for the inhalation of a formulation from a carrier. The carrier contains the formulation in a receptacle and is set oscillating by an air current. An improved or defined delivery and nebulisation of the preferably powdered formulation is made possible by the fact that the carrier is set oscillating in defined manner, the formulation is dispensed through a cover element having three to five holes and/or the air current flows onto a fin associated with the carrier and flows past at least substantially only one flat side of the carrier. ## Claims ### Claim 1 An inhaler (1) for the inhalation of a formulation (2) comprising a carrier (3) in the form of a belt, strip, blister or film, wherein: at a resting position, the carrier (3) is planar and extends longitudinally along a longitudinal axis, the carrier (3) comprises a free end, an opposing end, and a spring portion (4) located between the free end and the opposing end that is deformable by spring resilience, where the spring portion (4) includes a relatively stiff elastic characteristic that imparts a corresponding relative stiffness in the carrier (3), the carrier (3) includes an oblique fin (5) extending obliquely with respect to the longitudinal axis from the free end of the carrier (3) at least when the carrier is at the resting position, and the opposing end of the carrier (3) is fixed such that air current (L) flowing parallel to the longitudinal axis of the carrier (3) sets the free end of the carrier (3) into motion transversely with respect to the longitudinal axis, and the spring resilience of the spring portion (4) opposes the motion of the free end of the carrier (3) transversely with respect to the longitudinal axis and in combination with continued air current (L) sets the carrier into oscillation (S) by way of a resonance vibration established by the corresponding relative stiffness in the carrier (3) provided by the relatively stiff elastic characteristic of the spring portion (4). ### Claim 2 (depends on 1) The inhaler (1) according to claim 1, wherein the spring portion (4) comprises two spring bars (4A) extending parallel to one another and parallel to the longitudinal axis. ### Claim 3 (depends on 1) The inhaler (1) according to claim 1, characterized in that the spring portion (4) is in the form of a leaf and comprises an opening in the form of a slot or longitudinal slot (4B) extending parallel to the longitudinal axis. ### Claim 4 (depends on 1) The inhaler (1) according to claim 1, characterized in that the spring portion (4) extends at least substantially in a main plane of the carrier (3) or in a plane parallel thereto. ### Claim 5 (depends on 1) The inhaler (1) according to claim 1, further comprising: a housing (6) having an inlet (1B) at a first end and an outlet (1A) at an opposing, second end, wherein: at a resting position, the carrier (3) is planar and extends longitudinally within the housing (6) between the first and second ends of the housing (6) along the longitudinal axis, and the opposing end of the carrier (3) is connected to the housing (6) such that air current (L) entering and flowing through the inlet enters the housing (6) parallel to the longitudinal axis of the carrier (3) and impinges on the oblique fin (5) and sets the free end of the carrier (3) into motion transversely with respect to the longitudinal axis. ### Claim 6 (depends on 5) The inhaler (1) according to claim 5, characterized in that the spring portion (4) permits the carrier (3) to be movable at right-angles to the air current (L) but biases the carrier (3) back towards the resting position in the presence of the air current (L). ### Claim 7 (depends on 5) The inhaler (1) according to claim 5, characterized in that the carrier (3) is pivotable or movable about an axis (A) perpendicular to the longitudinal axis and located in a region of the spring portion (4). ### Claim 8 (depends on 5) The inhaler (1) according to claim 5, characterized in that: the carrier (3) is impacted by the air current (L) at least substantially only from the free end opposite to the spring portion (4), and/or the air current (L) flows along the carrier (3) at least substantially only parallel to a flat side and/or at least substantially only on a flat side of the carrier (3). ### Claim 9 (depends on 5) The inhaler (1) according to claim 5, characterized in that the oblique fin (5) onto which the air current (L) impinges is adjacent to the inlet (1B) of the inhaler (1). ### Claim 10 (depends on 5) The inhaler (1) according to claim 5, characterized in that the inhaler (1) comprises an opening device (7) for opening a holding chamber (3A) containing the formulation. ### Claim 11 (depends on 10) The inhaler (1) according to claim 10, characterized in that the opening device (7) is formed by a manually deformable wall of the housing (6) and/or comprises at least one piercing element (7A) that is resiliently and/or resettingly mounted. ### Claim 12 (depends on 5) The inhaler (1) according to claim 5, characterized in that the inhaler (1) comprises at least one stop (8, 9) for limiting the oscillation (S) of the carrier (3), the at least one stop (8, 9) being formed within the housing (6) of the inhaler (1). ### Claim 13 (depends on 5) The inhaler (1) according to claim 5, characterized in that the carrier (3) comprises a base element (3B) forming a receptacle (3A) for the formulation (2), and a cover (3D) over the receptacle (3A), wherein the cover (3D) is at least partially covered by a covering device (10) which can be manually opened or removed in order to open the carrier (3) or the cover (3D) for the subsequent dispensing of the formulation (2). ### Claim 14 (depends on 13) The inhaler (1) according to claim 13, characterized in that the covering device (10) comprises: a cover element (10A) having a first end coupled to a first peripheral edge of the base element (3B) closest to the outlet (1A) of the housing (6) and extending toward the inlet (1B) over the cover 3D and the receptacle (3A) past a second opposing edge of the base element (3B) closest to the inlet (1B), a folded-back portion of the cover element (10A) extending from the second opposing edge of the base element (3B) back over the cover element (10A), the cover (3D) and the receptacle (3A) and out through the outlet (1A), and an associated grip element (10B) for pulling the cover element (10A) out through the outlet (1A) and off the cover (3D). ### Claim 15 (depends on 13) The inhaler (1) according to claim 13, characterized in that the cover (3D) comprises a plurality of holes (3E) communicating with the formulation within the receptacle (3A), which holes (3E) are covered by the covering device (10) when the carrier (3) is closed. ### Claim 16 (depends on 5) The inhaler (1) according to claim 5, characterized in that the inhaler (1) is a single-use inhaler with the carrier (3) arranged within the housing (6). ### Claim 17 (depends on 1) The inhaler (1) according to claim 1, further comprising: a housing (6) having an inlet (1B) at a first end and an outlet (1A) at an opposing, second end; and a mouthpiece at the outlet (1A) of the housing, wherein: at a resting position, the carrier (3) is planar and extends longitudinally within the housing between the first and second ends of the housing (6) along the longitudinal axis, the carrier (3) comprises a base element (3B) forming a receptacle (3A) for the formulation (2), and a cover (3D) over the receptacle (3A), wherein the cover (3D) includes at least one opening and is at least partially covered by a covering device (10) which can be manually opened or removed in order to open the carrier (3) or the cover (3D) for the subsequent dispensing of the formulation (2), the covering device (10) comprises a cover element (10A) having a first end coupled to a first peripheral edge of the base element (3B) closest to the outlet (1A) of the housing (6) and extending toward the inlet (1B) over the cover 3D and the receptacle (3A) past a second opposing edge of the base element (3B) closest to the inlet (1B), the covering device (10) comprises a folded-back portion of the cover element (10A) extending from the second opposing edge of the base element (3B) back over the cover element (10A), the cover (3D) and the receptacle (3A) and out through the outlet (1A), and the covering device (10) comprises a grip element (10B) that projects out of the mouthpiece and the outlet (1A) for pulling the cover element (10A) off the cover (3D) and out through the outlet (1A) and out through the mouthpiece. ### Claim 18 (depends on 17) The inhaler (1) according to claim 17, characterized in that the cover (3D), which covers the receptacle (3A) containing the formulation (2), comprises, as the at least one opening, three to five holes (3E), which are covered by the covering device (10) when the carrier (3) is closed. ### Claim 19 (depends on 18) The inhaler (1) according to claim 18, characterized in that the holes (3E) are arranged in opposing end regions of the receptacle (3D).