# US 11,298,472 B2 · Ultrasonic nebulizer > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,298,472 B2 - Document ID: US11298472B2 - Status: Granted - Kind: B2 - Application number: 17/234,492 - Filed: 2021-04-19 - Published: 2021-10-28 - Granted: 2022-04-12 - Earliest claimed: 2020-04-24 - Applicants: SOSD Health & Medical Innovations Inc. - Inventors: Ali Sadeghinia; Ali Darbandi; Abbas Ostadalipour; Armin Sahba; Nasser Ashgriz - Web page: https://patentgrep.com/patent/US11298472B2 ## CPC - A61M 11/005: {using ultrasonics (spraying or atomising liquids using ultrasonic vibrations in general B05B17/06)} - A61M 11/001: {Particle size control} - A61M 15/001: {using ultrasonic means} - A61M 15/0021: {Mouthpieces therefor} - A61M 15/0085: {using ultrasonics (spraying or atomising liquids using ultrasonic vibrations in general B05B17/06)} - A61M 2205/0294: Piezoelectric materials - A61M 2205/8206: battery-operated - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract An ultrasonic nebulizer is provided that has a liquid chamber to receive a liquid. A piezoceramic transducer is attached to one end of the liquid chamber. The piezoceramic has an orifice to allow the liquid inside the chamber to exit. A plunger movably and sealbly is inserted into the liquid chamber from its other end, which is moved by a moving mechanism to push the liquid out of the liquid chamber. The plunger forms a small liquid droplet on the surface of the piezoceramic. Oscillation of the piezoceramic at megahertz frequencies results in atomization and formation of small droplets from the surface of the sessile droplet. The present nebulizer is a total consumption nebulizer, since all its droplets are substantially within 2 to 5 microns, which is the size range to penetrate into the lunges of a user. ## Claims ### Claim 1 A meshless ultrasonic nebulizer comprising: a liquid chamber having a proximal end, a distal end, and a volume to receive a liquid having a set of properties; a piezoceramic transducer having a planar top surface and a back surface and being operable in a range of 1-5 Mega Hertz frequency attached to the distal end of the liquid chamber, the piezoceramic transducer further consisting of an orifice at its center to allow for a liquid to enter from the liquid chamber into the orifice from the back surface and onto the top surface of the piezoceramic transducer to sustain a volume of a liquid on the top surface; a plunger movably and sealably inserted into the liquid chamber from its proximal end and is configured to move forward and backward inside the liquid chamber; a moving mechanism attached to the plunger to move the plunger; a drive circuit and a control system to control the operation of the moving mechanism and that of the piezoceramic transducer, and configured to move the plunger to force the liquid through the orifice of the piezoceramic transducer in order to form and continuously sustain a substantially hemispherical sessile droplet with a diameter in the range of 300 to 500 microns and a volume of less than 100 nanoliter on the top surface of the piezoceramic transducer, a power supply to provide power to the moving mechanism and the piezoceramic transducer, and wherein, a Mega Hertz vibration of the sessile droplet of less than 100 nanoliter generates an aerosol with droplet sizes of only less than 5 microns from a top surface of the sessile drop. ### Claim 2 (depends on 1) The ultrasonic nebulizer of claim 1, wherein the piezoceramic transducer is a circular and coated piezoceramic. ### Claim 3 (depends on 1) The ultrasonic nebulizer of claim 1, wherein the moving mechanism comprises of a motor that rotates a screw shaft in both clockwise and counterclockwise rotational directions, and wherein the screw shaft is connected to a moving rod through a connecting rod, and wherein the moving rod is connected to the plunger, whereby the clockwise and counterclockwise rotations of the screw shaft can move the plunger forward and backward. ### Claim 4 (depends on 1) The ultrasonic nebulizer of claim 1, wherein the moving mechanism comprises of a motor that moves a central shaft backward and forward, and wherein the central shaft is connected to the plunger, whereby the movement of the central shaft can move the plunger forward and backward. ### Claim 5 (depends on 1) The ultrasonic nebulizer of claim 1, wherein the moving mechanism is a linear motion motor. ### Claim 6 (depends on 1) The ultrasonic nebulizer of claim 1, wherein the diameter of the orifice is less than 500 microns. ### Claim 7 (depends on 1) The ultrasonic nebulizer of claim 1, wherein the nebulizer is substantially cylindrical comprising of a cylindrical liquid chamber. ### Claim 8 (depends on 1) The ultrasonic nebulizer of claim 1, further having a housing to house a set of nebulizer components and having an attachable mouth piece that has an aerosol port. ### Claim 9 (depends on 1) The ultrasonic nebulizer of claim 1, wherein the nebulizer has air inlets and air channels to allow an inlet air to enter the nebulizer and pass through the air channels to reach the mouth piece and mix with the aerosol generated by the piezoceramic transducer. ### Claim 10 (depends on 9) The ultrasonic nebulizer of claim 9, further having air filters to filter the inlet air. ### Claim 11 (depends on 1) The ultrasonic nebulizer of claim 1, further having an air swirler to swirl the air before entering the mouth piece. ### Claim 12 (depends on 1) The ultrasonic nebulizer of claim 1, further having an ON/OFF switch to control a duration of the ON time. ### Claim 13 (depends on 1) The ultrasonic nebulizer of claim 1, wherein the power supply is a rechargeable battery. ### Claim 14 (depends on 1) The ultrasonic nebulizer of claim 1, wherein the control system is configured to provide a variable frequency and variable power signal to the piezoceramic transducer. ### Claim 15 A meshless ultrasonic nebulizer comprising: a casing having a first section and a second section, wherein the first section has a set of air inlets to allow air to enter into the casing, and the second section is an elongated section that has an opening configured to receive a mouth piece and allows air to exit the casing; a liquid chamber placed inside the elongated section of the second section of the casing and having a proximal end, a distal end, and a volume to receive a liquid having a set of properties, and wherein the distal end is aligned towards the opening of the casing; a piezoceramic transducer consisting of an orifice at its center and attached to the distal end of the liquid chamber, wherein the piezoelectric is operable in a range of 1-5 Mega Hertz frequency, wherein a back side of the piezoceramic transducer faces the liquid and a front planar side of the piezoceramictransducer faces the opening of the casing; a plunger movably and sealably inserted into the liquid chamber from its proximal end and is configured to move forward and backward inside the liquid chamber; a motor placed in the first section of the casing that rotates a screw shaft in both clockwise and counterclockwise rotational directions; a connecting rod connecting the screw shaft to the plunger, whereby the clockwise and counterclockwise rotations of the screw shaft moves the plunger forward and backward; a drive circuit and a control system to control the operation of the motor and the piezoceramic transducer, and configured to move the plunger to force the liquid through the orifice of the piezoceramic transducer in order to form and continuously sustain a substantially hemispherical sessile droplet with a diameter in the range of 300 to 500 microns and a volume of less than 100 nanoliter on the top surface of the piezoceramic transducer, wherein a Mega Hertz vibration of the sessile droplet of less than 100 nanoliter generates an aerosol with droplet sizes of only less than 5 microns from a top surface of the sessile drop; a battery placed inside the casing and connected to an ON/OFF switch placed on a side of the casing to provide powerto the motor and the piezoceramic transducer and to control a duration of the ON time, and an air swirler set around the liquid chamber and in the elongated section of the casing to swirl the air that enters the casing through the set of air inlets before entering the mouth piece, thereby keeping the aerosol at the center of the mouth piece, preventing any wall collisions.