# US 11,298,462 B2 · Automatic injection system

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- Number: US 11,298,462 B2
- Document ID: US11298462B2
- Status: Granted
- Kind: B2
- Application number: 16/962,739
- Filed: 2020-03-06
- Published: 2021-09-09
- Granted: 2022-04-12
- Earliest claimed: 2019-03-15
- Assignees: Eli Lilly and Company
- Applicants: Eli Lilly and Company
- Inventors: William Godwin Atterbury; Joseph Daniel Dennis, Jr.; Brian Charles Kelley; Mark Lafever; Steven Michael Madland; Andrew Thomas Snow; Jessica Diane Young
- Web page: https://patentgrep.com/patent/US11298462B2

## CPC

- A61M 5/2033: {Spring-loaded one-shot injectors with or without automatic needle insertion (multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287)}
- A61M 5/283: {by telescoping of ampoules or carpules with the syringe body}
- A61M 5/3148: {Means for causing or aiding aspiration or plunger retraction}
- A61M 5/31513: {Piston constructions to improve sealing or sliding}
- A61M 5/31581: {the component being manually operated or triggered by a rotating or pivoting actuator operated by user, e.g. an injection lever or handle}
- A61M 5/32: Needles; Details of needles pertaining to their connection with syringe or hub (infusion needles A61M5/158); Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M 5/206: {with automatic needle insertion}
- A61M 2005/2073: {preventing premature release, e.g. by making use of a safety lock}
- A61M 2005/2086: {having piston damping means, e.g. axially or rotationally acting retarders}
- A61M 2005/2418: {comprising means for damping shocks on ampoule}
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}

## Abstract

An automatic injection device is provided, where the device includes a syringe carrier and a retraction assembly. The syringe carrier includes two identical parts that are discrete from one another and interlock with one another. The retraction assembly includes a shuttle and a follower, the follower having a moveable latch. The follower has a coupled configuration in which the latch is biasedly coupled to the shuttle, and a decoupled configuration in which the latch is in sliding engagement with a curvilinear surface of the shuttle.

## Claims

### Claim 1

An automatic injection device, comprising:
a housing comprising a proximal end and a distal end;
a syringe including a needle, a syringe body and a plunger, the syringe being moveable within the housing from a first position to a second position that is distal to the first position to move the needle toward the distal end of the housing, and the plunger being moveable relative to the syringe body to expel medication from the syringe body through the needle;
a shuttle having a distal surface comprising a shuttle protrusion and a curvilinear surface, the curvilinear surface extending from the shuttle protrusion to define an undercut region, at least a portion of the distal surface being made of a lubricant-infused material; and
a follower having a follower body and a latch, the latch having a cantilevered arm being moveable relative to the follower body and relative to the shuttle protrusion, the cantilevered arm with an end having a latch protrusion, wherein the latch protrusion has a straight leading surface and a curved trailing surface;
wherein:
the follower has a coupled configuration in which the latch is biasedly coupled over the shuttle protrusion and the straight leading surface of the latch protrusion is in contact with the shuttle protrusion, and
the follower has a decoupled configuration in which the latch has cleared the shuttle protrusion and the curved trailing surface of the latch protrusion is in sliding engagement with the curvilinear surface, the follower is rotatable relative to the shuttle, and the shuttle is moveable toward the proximal end of the housing to retract the syringe.

### Claim 2 (depends on 1)

The automatic injection device of claim 1, wherein the lubricant-infused material comprises silicone.

### Claim 3 (depends on 1)

The automatic injection device of claim 1, wherein the entire shuttle is made of the lubricant-infused material.

### Claim 4 (depends on 1)

The automatic injection device of claim 1, further comprising a spring that is compressed between the shuttle and the follower when the follower is in the coupled configuration.

### Claim 5 (depends on 4)

The automatic injection device of claim 4, wherein the spring is torsionally pre-loaded when the follower is in the coupled configuration.

### Claim 6 (depends on 1)

The automatic injection device of claim 1, wherein the shuttle is moveable toward the proximal end of the housing after the follower has rotated through a predetermined angle of rotation.

### Claim 7 (depends on 1)

The automatic injection device of claim 1, wherein the syringe body contains a medication.

### Claim 8 (depends on 1)

The automatic injection device of claim 1, further comprising a syringe carrier including a first part and a second part that are discrete from one another and interlocked together, each of the first and second parts comprising a proximal flange surface, a distal flange surface, a circumferential rounded wall between the proximal flange surface and the distal flange surface, and a gap located between the proximal flange surface, the distal flange surface and the circumferential rounded wall, wherein a portion of the syringe body is received within the gap, wherein the shuttle is engageable with the syringe carrier during proximal movement.

### Claim 9 (depends on 8)

The automatic injection device of claim 8, wherein the syringe carrier includes a cushion, the proximal flange surface and the distal flange surface having a greater material hardness than the cushion.

### Claim 10 (depends on 9)

The automatic injection device of claim 9, wherein the syringe body includes a syringe body flange, and the cushion is in contact with the syringe body flange.

### Claim 11 (depends on 10)

The automatic injection device of claim 10, wherein the cushion includes at least one cushion protrusion contacting the syringe body underneath the syringe body flange, wherein the at least one cushion protrusion is disposed adjacent to an end of an inner radial surface of the cushion of each of the first and second parts.

### Claim 12 (depends on 8)

The automatic injection device of claim 8, wherein the syringe body includes a syringe body flange, wherein the circumferential rounded wall of the syringe carrier partially surrounds an outer perimeter of the syringe body flange, and said proximal flange surface of each of the parts together fully overlap a proximal surface of the syringe body flange.

### Claim 13

An automatic injection device, comprising:
a housing comprising a proximal end and a distal end;
a syringe including a needle, a syringe body and a plunger, the syringe being axially moveable within the housing from a first position to a second position that is distal to the first position to move the needle toward the distal end of the housing, and the plunger being axially moveable relative to the syringe body to expel medication from the syringe body through the needle;
a shuttle coupled to the syringe, the shuttle having a distal surface comprising a shuttle protrusion and a curvilinear surface, the curvilinear surface extending from the shuttle protrusion to define an undercut region; and
a follower having a follower body and a latch, the latch being moveable relative to the follower body and relative to the shuttle protrusion, the latch comprising a latch protrusion, the latch protrusion having a straight leading surface and a curved trailing surface;
wherein:
the follower has a coupled configuration in which the latch of the follower is biasedly coupled with the shuttle protrusion to inhibit rotation of the follower, the straight leading surface of the latch protrusion is in contact with the shuttle protrusion, and
the follower has a decoupled configuration in which the latch protrusion has cleared the shuttle protrusion and the curved trailing surface of the latch protrusion is in sliding engagement with the curvilinear surface of the shuttle as the follower is rotated relative to the shuttle, the shuttle axially moveable toward the proximal end of the housing to retract the syringe after the follower has rotated through a predetermined angle of rotation.

### Claim 14 (depends on 13)

The automatic injection device of claim 13, wherein the distal surface of the shuttle is made of a lubricant-infused material.

### Claim 15 (depends on 13)

The automatic injection device of claim 13, further comprising a syringe carrier including a first part and a second part that are discrete from one another and interlocked together, each of the first and second parts comprising a proximal flange surface, a distal flange surface, a circumferential rounded wall between the proximal flange surface and the distal flange surface, and a gap located between the proximal flange surface, the distal flange surface and the circumferential rounded wall, wherein the syringe body comprises a syringe flange that is received within the gap, wherein the shuttle is engaged with the syringe carrier during proximal movement when the syringe being retracted.

### Claim 16 (depends on 15)

The automatic injection device of claim 15, wherein the syringe carrier includes a cushion, the proximal flange surface and the distal flange surface having a greater material hardness than the cushion, wherein the cushion is in contact with the syringe flange.

### Claim 17 (depends on 13)

The automatic injection device of claim 13, further comprising a spring that is compressed between the shuttle and the follower when the follower is in the coupled configuration.

### Claim 18 (depends on 17)

The automatic injection device of claim 17, wherein the spring is torsionally pre-loaded when the follower is in the coupled configuration, and the spring urges rotation of the follower relative to the shuttle when the follower is in the decoupled configuration.

### Claim 19 (depends on 13)

The automatic injection device of claim 13, wherein the syringe body contains a medication.
