# US 11,298,458 B2 · Drug delivery device > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,298,458 B2 - Document ID: US11298458B2 - Status: Granted - Kind: B2 - Application number: 15/760,879 - Filed: 2016-09-05 - Published: 2019-03-21 - Granted: 2022-04-12 - Earliest claimed: 2015-09-18 - Assignees: Sanofi-Aventis Deutschland GmbH - Applicants: Sanofi-Aventis Deutschland GmbH - Inventors: Andreas Bode - Web page: https://patentgrep.com/patent/US11298458B2 ## CPC - A61M 5/1454: {spring-actuated, e.g. by a clockwork} - A61M 5/145: using pressurised reservoirs, e.g. by means of pistons - A61M 5/1452: {pressurised by means of pistons} - A61M 5/24: Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or cartridges, e.g. automatic - A61M 5/162: Needle sets, i.e. connections by puncture between reservoir and tube - A61M 2005/14506: {mechanically driven, e.g. spring or clockwork} - A61M 2005/2433: {Ampoule fixed to ampoule holder} - A61M 2205/8206: battery-operated - A61M 2207/00: Methods of manufacture, assembly or production - A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)} ## Abstract The present disclosure relates to a drug delivery device for dispensing of a liquid medicament, the device comprising: a housing to accommodate a cartridge filled with the medicament and having a piston slidably displaced inside the cartridge and sealing a proximal end of the cartridge, at least one resilient member having a first end arranged at an inside facing side wall portion of the housing and having a second end (opposite to the first end to abut with the piston of the cartridge. ## Claims ### Claim 1 A drug delivery device for dispensing of a liquid medicament, the drug delivery device comprising: a housing to accommodate a cartridge filled with the liquid medicament and having a piston slidably displaced inside the cartridge and sealing the cartridge; a resilient member having a first end arranged at an inside facing side wall portion of the housing and having a second end opposite to the first end to abut the piston of the cartridge; and an electronic suction pump to connect to a distal end of the cartridge for a suction-based extraction of the liquid medicament from the cartridge. ### Claim 2 (depends on 1) The drug delivery device according to claim 1, wherein the first end of the resilient member is firmly attached to the side wall portion of the housing. ### Claim 3 (depends on 1) The drug delivery device according to claim 1, wherein the resilient member protrudes substantially perpendicular from the side wall portion, and the second end extends into an interior of the housing. ### Claim 4 (depends on 1) The drug delivery device according to claim 1, further comprising a pressure piece attached to the second end of the resilient member, wherein the pressure piece is complementary shaped to a cross section of the piston. ### Claim 5 (depends on 1) The drug delivery device according to claim 1, wherein the resilient member is integrally formed with the side wall portion. ### Claim 6 (depends on 1) The drug delivery device according to claim 1, wherein the resilient member comprises a compression spring. ### Claim 7 (depends on 1) The drug delivery device according to claim 1, wherein the resilient member is made of a plastic material, an elastomeric material, or a combination thereof. ### Claim 8 (depends on 1) The drug delivery device according to claim 1, further comprising a tube with a connector to establish a fluid transferring interconnection with an interior of the cartridge. ### Claim 9 (depends on 1) The drug delivery device according to claim 1, further comprising the cartridge firmly assembled inside the housing with the piston axially abutting the resilient member, wherein a magnitude of a force exerted by the resilient member onto the piston is smaller than or substantially equal to a breakaway force necessary to displace the piston relative to a barrel of the cartridge when the piston is initially resting. ### Claim 10 (depends on 1) The drug delivery device according to claim 1, wherein the side wall portion of the housing is pivotably or detachably connected to another portion of the housing. ### Claim 11 (depends on 10) The drug delivery device according to claim 10, wherein: the side wall portion forms a lid to cover an access opening of the housing, a first end of the lid is pivotably attached to the other portion of the housing via a hinge, and a second end of the lid comprises a fastener to releasably engage with a complementary shaped fastening structure of the housing when in a closed configuration in which the lid covers the access opening. ### Claim 12 (depends on 1) The drug delivery device according to claim 1, wherein the housing comprises a reusable housing part and a disposable housing part that are detachably connectable. ### Claim 13 (depends on 12) The drug delivery device according to claim 12, wherein the cartridge is assembled inside the disposable housing part. ### Claim 14 (depends on 12) The drug delivery device according to claim 12, wherein the first end of the resilient member is attached to the reusable housing part or to the disposable housing part. ### Claim 15 A method of assembling a drug delivery device, the drug delivery device comprising a housing to accommodate a cartridge filled with the liquid medicament and having a piston slidably displaced inside the cartridge and sealing the cartridge, a resilient member having a first end arranged at an inside facing side wall portion of the housing and having a second end opposite to the first end to abut the piston of the cartridge, and an electronic suction pump to connect to a distal end of the cartridge for a suction-based extraction of the liquid medicament from the cartridge, the method comprising: inserting the cartridge into an opening of the housing of the drug delivery device; and placing a sidewall portion of the housing into a closed configuration to cover the opening and cause the second end of the resilient member of the drug delivery device to abut the piston of the cartridge. ### Claim 16 (depends on 15) The method of claim 15, wherein the sidewall portion comprises a pivotable lid, wherein placing the sidewall portion of the housing into the closed configuration comprises closing the lid to cover the opening and cause the resilient member of the drug delivery device to abut the piston of the cartridge. ### Claim 17 (depends on 15) The method of claim 15, wherein placing the sidewall portion of the housing into the closed configuration comprises causing the resilient member to exert a magnitude of force onto the piston smaller than or substantially equal to a breakaway force necessary to displace the piston relative to a barrel of the cartridge when the piston is initially resting. ### Claim 18 (depends on 15) The method of claim 15, wherein inserting the cartridge into the opening of the housing comprises placing the cartridge into fluid communication with a suction pump configured to deliver medicament from the cartridge. ### Claim 19 (depends on 15) The method of claim 15, wherein: inserting the cartridge into the opening of the housing comprises inserting the cartridge into a disposable portion of the housing, and the resilient member is arranged on the disposable portion or a reusable portion of the housing. ### Claim 20 A drug delivery device for dispensing of a liquid medicament, the drug delivery device comprising: a housing to accommodate a cartridge filled with the liquid medicament and having a piston slidably displaced inside the cartridge and sealing the cartridge; a resilient member having a first end arranged at an inside facing side wall portion of the housing and having a second end opposite to the first end to abut the piston of the cartridge; a suction pump to connect to a distal end of the cartridge for a suction-based extraction of the liquid medicament from the cartridge; and a tube with a connector to establish a fluid transferring interconnection with an interior of the cartridge, wherein the tube extends through the suction pump and is connected to a dispensing outlet to allow the liquid medicament, transported through the tube, to be directly injected into a biological tissue.