Quail egg allergy antigen
AssigneeHoyu Co., Ltd.
InventorsKayoko Matsunaga, Akiko Yagami, Yasuto Kondo, Kazuhiro Hara, Masashi Nakamura, Yuji Aoki
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Abstract
The present invention provides novel antigens of an allergy to a quail egg, methods and kits for diagnosing an allergy to a quail egg, pharmaceutical compositions comprising such an antigen, and quail eggs or processed products of quail egg which are devoid of such an antigen.
Claims6
A quail-derived antigen, wherein said quail-derived antigen is a protein:
- (1B) comprising at least one amino acid sequence selected from the group consisting of SEQ ID NOs:
- 1, 4, 6, 8-10, 12-14 and 18;
- or,
- (2B) comprising at least one amino acid sequence selected from the group consisting of SEQ ID NOs:
- 19, 21, 22 and 24,
- and is causative of allergy to quail egg,
- wherein said quail-derived antigen is immobilized to a carrier or a surface.
A kit, comprising a quail-derived antigen, wherein said quail-derived antigen is a protein:
- (1B) comprising at least one amino acid sequence selected from the group consisting of SEQ ID NOs:
- 1, 4, 6, 8-10, 12-14 and 18;
- or,
- (2B) comprising at least one amino acid sequence selected from the group consisting of SEQ ID NOs:
- 19, 21-22 and 24,
- and is causative of allergy to quail egg,
- wherein said quail-derived antigen is immobilized to a carrier or a surface.
A kit, comprising:
- (i) a quail-derived antigen, wherein said quail-derived antigen is a protein:
- (1B) comprising at least one amino acid sequence selected from the group consisting of SEQ ID NOs:
- 1, 4, 6, 8-10, 12-14 and 18;
- or,
- (2B) comprising at least one amino acid sequence selected from the group consisting of SEQ ID NOs:
- 19, 21-22 and 24,
- and is causative of allergy to quail egg, and,
- (ii) an antibody which detects binding between said quail-derived antigen and an IgE antibody that specifically binds to the quail-derived antigen;
- wherein said quail-derived antigen is immobilized to a carrier or a surface.
A kit, comprising:
- (i) a quail-derived antigen, wherein said quail-derived antigen is a protein:
- (1B) comprising at least one amino acid sequence selected from the group consisting of SEQ ID NOs:
- 1, 4, 6, 8-10, 12-14 and 18;
- or,
- (2B) comprising at least one amino acid sequence selected from the group consisting of SEQ ID NOs:
- 19, 21-22 and 24,
- and is causative of allergy to quail egg, and,
- (ii) a secondary antibody specific for IgE antibody that specifically binds to the quail-derived antigen;
- wherein said quail-derived antigen is immobilized to a carrier or a surface.
A composition comprising a quail-derived antigen, wherein said quail-derived antigen is a protein:
- (1B) comprising at least one amino acid sequence selected from the group consisting of SEQ ID NOs:
- 1, 4, 6, 8-10, 12-14 and 18;
- or,
- (2B) comprising at least one amino acid sequence selected from the group consisting of SEQ ID NOs:
- 19, 21-22 and 24,
- and is causative of allergy to quail egg,
- wherein said quail-derived antigen is immobilized to a carrier or a surface.
Dependencies are inferred from the claim text.