# US 11,298,374 B2 · Methods for improving respiratory system health and increasing the concentration of hypothiocyanate ion in vertebrate lungs

> Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt

- Number: US 11,298,374 B2
- Document ID: US11298374B2
- Status: Granted
- Kind: B2
- Application number: 16/431,032
- Filed: 2019-06-04
- Published: 2019-11-07
- Granted: 2022-04-12
- Earliest claimed: 2013-08-20
- Applicants: James D. Lee
- Inventors: James D. Lee
- Web page: https://patentgrep.com/patent/US11298374B2

## CPC

- A61K 33/40: Peroxides
- A61L 2/208: Hydrogen peroxide
- A61L 9/04: using substances evaporated in the air without heating
- A61L 2202/11: Apparatus for generating biocidal substances, e.g. vaporisers, UV lamps
- A61L 2209/211: Use of hydrogen peroxide, liquid and vaporous
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61L: METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES (preservation of bodies or disinfecting characterised by the agents employed A01N; preserving, e.g. sterilising, food or foodstuffs A23; preparations for medical, dental or toiletry purposes A61K)

## Abstract

The present disclosure relates to methods and devices to improve respiratory system health, increase resistance to infection, and increase the hypothiocyanate ion in mammalian lungs. The methods generally comprise: generating a Hydrogen Peroxide Gas that is non-hydrated and free of ozone, and directing the gas comprising primarily Hydrogen Peroxide Gas into an environment and exposing a subject to the environment such that the Hydrogen Peroxide Gas acts to the increase of the hypothiocyanate ion in mammalian lungs.

## Claims

### Claim 1

A method for treating a respiratory illness in a subject in need thereof comprising:
providing an enclosed space for treatment comprising a purified hydrogen peroxide gas (PHPG) that is substantially free of hydration and ozone at a final concentration of at least 0.01 parts per million (ppm); and
treating said subject in need by exposing said subject to said environment for at least one period of time to provide a therapeutic amount of PHPG, wherein said treating reduces the severity of a respiratory infection or reduces the duration of a respiratory infection wherein said subject in need thereof is a human and is infected by an influenza virus, a severe acute respiratory syndrome (SARS) virus, a Middle East Respiratory Syndrome (MERS) virus, or a respiratory syncytial virus (RSV), wherein said subject in need has a respiratory infection.

### Claim 2 (depends on 1)

The method of claim 1, wherein said reduction of the severity of respiratory infections is a reduction in one or more of nasal congestion, runny nose (rhinorrhea), nasal discharge, nasal breathing, sneezing, sore or scratchy throat, painful swallowing (odynophagia), cough, malaise, or fever.

### Claim 3 (depends on 1)

The method of claim 1, wherein said treating comprises reducing the duration of said respiratory infection.

### Claim 4 (depends on 1)

The method of claim 1, wherein said period time is at least 8 hours over a 7 day period.

### Claim 5 (depends on 1)

The method of claim 1, wherein the total time of exposure is at least 1 hours.

### Claim 6 (depends on 1)

The method of claim 1, wherein said exposing is repeated 1 or more times daily, weekly, bi-weekly, or monthly.

### Claim 7 (depends on 1)

The method of claim 1, wherein said environment comprises PHPG at a final concentration of at least 0.1 ppm.

### Claim 8 (depends on 1)

The method of claim 1, wherein said therapeutic amount is at least 0.1 units of PHPG.

### Claim 9 (depends on 1)

The method of claim 1, wherein said therapeutic amount is at least 0.5 units of PHPG.

### Claim 10 (depends on 1)

The method of claim 1, wherein said therapeutic amount is provided at least once per day.