# US 11,298,264 B2 · Intraocular shunt implantation

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- Number: US 11,298,264 B2
- Document ID: US11298264B2
- Status: Granted
- Kind: B2
- Application number: 16/509,458
- Filed: 2019-07-11
- Published: 2019-11-21
- Granted: 2022-04-12
- Earliest claimed: 2013-06-28
- Assignees: AqueSys, Inc.
- Applicants: AqueSys, Inc.
- Inventors: Christopher Horvath; Laszlo O. Romoda; Richard A. Lewis
- Web page: https://patentgrep.com/patent/US11298264B2

## CPC

- A61F 9/00781: {Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment (drainage implants in general A61M27/002)}
- A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C)

## Abstract

Glaucoma can be treated by implanting an intraocular shunt in the eye. The implantation can be performed by first determining an entry area below a corneal limbus of an eye. Thereafter, the intraocular shunt can be inserted into eye tissue through the entry area such that an inflow end of the shunt is positioned in the anterior chamber of the eye and an outflow end of the shunt is positioned between layers of Tenon's capsule.

## Claims

### Claim 1

A method of treating glaucoma comprising determining an entry area posterior to a corneal limbus of an eye and inserting an intraocular shunt into eye tissue through the entry area such that an inflow end of the shunt is positioned in the anterior chamber of the eye and an outflow end of the shunt is positioned between layers of Tenon's capsule.

### Claim 2 (depends on 1)

The method of claim 1, wherein inserting an intraocular shunt into eye tissue comprises forming a passageway through the sclera.

### Claim 3 (depends on 1)

The method of claim 1, wherein a device for deploying the intraocular shunt comprises a shaft configured to hold the shunt, and wherein the inserting comprises advancing the shaft through the sclera until reaching a first position at which a bevel of the shaft is positioned in the anterior chamber of the eye.

### Claim 4 (depends on 3)

The method of claim 3, wherein after reaching the first position, the inserting comprises advancing a pusher component of the device such that the shunt is pushed distally out of the shaft.

### Claim 5 (depends on 4)

The method of claim 4, wherein the advancing the pusher component comprises pushing less than an entire length of the shunt distally out of the shaft.

### Claim 6 (depends on 4)

The method of claim 4, wherein the device comprises a sleeve having a distal end and a lumen, the shaft being disposed within the lumen, wherein the inserting further comprises advancing the pusher component to a distal most position at which a distal end of the pusher component is positioned longitudinally proximal to the sleeve distal end.

### Claim 7 (depends on 4)

The method of claim 4, wherein the device comprises a sleeve having a distal end and a lumen, the shaft being disposed within the lumen, and wherein at the first position, the sleeve distal end is spaced apart from the eye tissue.

### Claim 8 (depends on 7)

The method of claim 7, wherein the inserting further comprises advancing the pusher component until a distal end of the pusher component is positioned longitudinally adjacent to the sleeve distal end.

### Claim 9 (depends on 7)

The method of claim 7, wherein the sleeve distal end is spaced apart from anterior chamber angle tissue in the first position.

### Claim 10 (depends on 7)

The method of claim 7, wherein the inserting further comprises, while maintaining the shaft substantially fixed relative to the sclera, advancing the sleeve distally over the shaft until the sleeve distal end contacts eye tissue.

### Claim 11 (depends on 10)

The method of claim 10, wherein after the sleeve distal end contacts the eye tissue, the inserting further comprises proximally withdrawing the shaft from the sclera until the bevel is received within a lumen of the sleeve.

### Claim 12 (depends on 4)

The method of claim 4, wherein the device comprises a sleeve having a distal end comprising a beveled shape that corresponds with an anatomical angle of the entry area surface of the eye.

### Claim 13

A method of treating glaucoma comprising determining an entry area posterior to a corneal limbus of an eye and inserting an intraocular shunt into eye tissue through the entry area such that first end of the shunt is positioned in the anterior chamber of the eye and a second end of the shunt is positioned between layers of Tenon's capsule.

### Claim 14 (depends on 13)

The method of claim 13, wherein a device for deploying the intraocular shunt comprises a shaft configured to hold the shunt, and wherein the inserting comprises advancing the shaft through the sclera until reaching a first position at which a distal end of the shaft is positioned in the anterior chamber of the eye.

### Claim 15 (depends on 14)

The method of claim 14, wherein after reaching the first position, the inserting comprises advancing a pusher component of the device such that the shunt is pushed distally out of the shaft.

### Claim 16 (depends on 15)

The method of claim 15, wherein the advancing the pusher component comprises pushing less than an entire length of the shunt distally out of the shaft.

### Claim 17

An ab externo intraocular shunt insertion technique wherein the shunt enters an eye via the sclera and is positioned so as to extend from the anterior chamber of the eye to a region between layers of Tenon's capsule.

### Claim 18 (depends on 17)

The method of claim 17, wherein a device for deploying the intraocular shunt comprises a shaft configured to hold the shunt, and wherein the inserting comprises advancing the shaft through the sclera until reaching a first position at which a distal end of the shaft is positioned in the anterior chamber of the eye.

### Claim 19 (depends on 18)

The method of claim 18, wherein after reaching the first position, the inserting comprises advancing a pusher component of the device such that the shunt is pushed distally out of the shaft.

### Claim 20 (depends on 19)

The method of claim 19, wherein the advancing the pusher component comprises pushing less than an entire length of the shunt distally out of the shaft.
