# US 11,298,232 B2 · Cranial implant with dural window

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- Number: US 11,298,232 B2
- Document ID: US11298232B2
- Status: Granted
- Kind: B2
- Application number: 16/721,392
- Filed: 2019-12-19
- Published: 2020-06-25
- Granted: 2022-04-12
- Earliest claimed: 2018-12-19
- Assignees: Longeviti Neuro Solutions LLC
- Applicants: Longeviti Neuro Solutions LLC
- Inventors: Jesse Christopher; Bradley Rabinovitz; Chad R. Gordon
- Web page: https://patentgrep.com/patent/US11298232B2

## CPC

- A61F 2/2875: {Skull or cranium (A61F2/2803 takes precedence; joints for temporo-mandibular [TM] joints [TMJ] A61F2/3099)}
- A61B 5/0059: {using light, e.g. diagnosis by transillumination, diascopy, fluorescence (photoacoustic A61B5/0093; optical measurement of heart rate A61B5/02416; optical measurement of blood flow A61B5/0261; optical measurement of analytes A61B5/1455)}
- A61B 5/4064: {Evaluating the brain (for intracranial pressure A61B5/031; for cerebral blood gases A61B5/14553; using EEG A61B5/369)}
- A61F 2/30749: {Fixation appliances for connecting prostheses to the body}
- A61F 2/30942: {for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques}
- A61B 2017/00907: {for light}
- A61B 2017/0092: {for X-rays}
- A61B 2017/00924: {for ultrasonic waves}
- A61B 2090/103: {Cranial plugs for access to brain}
- A61B 2090/3966: {Radiopaque markers visible in an X-ray image}
- A61F 2002/3008: {radio-opaque, e.g. radio-opaque markers}
- A61F 2002/3009: {Transparent or translucent}
- A61F 2002/30092: {using shape memory or superelastic materials, e.g. nitinol}
- A61F 2002/30617: {Visible markings for adjusting, locating or measuring}
- A61F 2310/00353: Bone cement, e.g. polymethylmethacrylate or PMMA
- A61N 1/0529: {Electrodes for brain stimulation}
- A61F: FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS (dental prosthetics A61C)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)

## Abstract

A cranial implant for access to a cerebral cortex includes a window member shaped and dimensioned for positioning within a dural defect to provide access through the dura such that access to the cerebral cortex is provided in a location under study. An implant body is provided having a geometry that substantially conforms to a resected portion of a patient's anatomy to which the implant body is to be secured.

## Claims

### Claim 1

A cranial implant for providing visual, optical, ultrasonic, or radiofrequency access to a cerebral cortex of a patient, the cranial implant comprising:
a window member shaped and dimensioned for positioning within a dural defect defined by an opening formed within dura mater of a patient to provide access to the cerebral cortex, the window member being radiolucent, sonolucent, or visually transparent, the window member further including an upper first surface, a lower second surface opposite the upper first surface, and a peripheral edge extending between the upper first surface and the lower second surface; and
an intercranial implant body shaped and dimensioned for integration into the patient's skull such that it has a geometry that is capable of conforming to a resected portion of the patient's anatomy to which the implant body is to be secured,
wherein the intercranial implant body is radiolucent, sonolucent, or visually transparent, and
wherein the intercranial implant body includes an upper first surface, a lower second surface opposite the upper first surface which is engaged with the upper first surface of the window member, and a peripheral edge extending between the upper first surface and the lower second surface, wherein the lower second surface is engaged with the upper first surface of the window member, such that the window member in positioned under the intercranial implant body;
wherein the intercranial implant body includes at least one implant body etching and the window member includes a window etching, wherein when viewed from a specific location, the window etching and at least one implant body etching merge into a single, location-identifying image on a brain of the patient.

### Claim 2 (depends on 1)

The cranial implant according to claim 1, wherein the at least one implant body etching and the window etching include radiographic materials.

### Claim 3 (depends on 1)

The cranial implant according to claim 1, wherein the at least one implant body etching includes a first outer implant body etching and a second outer implant body etching respectively formed along outer and inner surfaces of the implant body.

### Claim 4 (depends on 1)

The cranial implant according to claim 1, wherein the intercranial implant body is made of clear Poly(methyl methacrylate)(PMMA).

### Claim 5 (depends on 1)

The cranial implant according to claim 1, further including a coupling ring securing the window member within the opening formed within the dura mater of the patient.

### Claim 6 (depends on 5)

The cranial implant according to claim 5, wherein the coupling ring is made of a shape memory material.

### Claim 7 (depends on 1)

The cranial implant according to claim 1, wherein the window member and the intercranial implant body are separate and distinct elements.

### Claim 8 (depends on 7)

The cranial implant according to claim 7, wherein mating hooks and/or latching structures secure the window member to the intercranial implant body.

### Claim 9 (depends on 1)

The cranial implant according to claim 1, wherein the window member is sonolucent allowing for passage of ultrasonic waves therethrough.

### Claim 10 (depends on 1)

The cranial implant according to claim 1, wherein the window member is optically clear in the visible light spectrum allowing for optical and/or visual access therethrough.
