# US 11,298,026 B2 · Imaging techniques using an imaging guidewire

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- Number: US 11,298,026 B2
- Document ID: US11298026B2
- Status: Granted
- Kind: B2
- Application number: 16/400,622
- Filed: 2019-05-01
- Published: 2019-08-22
- Granted: 2022-04-12
- Earliest claimed: 2013-10-04
- Applicants: Phyzhon Health Inc.
- Inventors: Howard Neil Rourke; Michael J. Eberle; Diana Margaret Tasker
- Web page: https://patentgrep.com/patent/US11298026B2

## CPC

- A61B 5/0095: {by applying light and detecting acoustic waves, i.e. photoacoustic measurements}
- A61B 1/0017: {Details of single optical fibres, e.g. material or cladding}
- A61B 5/0084: {for introduction into the body, e.g. by catheters (A61B5/1459 takes precedence)}
- A61B 5/0097: {by applying acoustic waves and detecting light, i.e. acousto-optic measurements}
- A61B 5/6851: {Guide wires}
- A61B 5/7203: {for noise prevention, reduction or removal}
- A61B 5/742: {using visual displays (displays for heart-related electrical signals, e.g. ECG, A61B5/339)}
- G01H 9/004: {using fibre optic sensors (light guides per se G02B6/00, acousto-optical devices specially adapted for gating or modulating in optical wave guides G02F1/125)}
- G02B 6/29319: {With a cascade of diffractive elements or of diffraction operations (forming interferometer by splitting and recombining G02B6/29347 - G02B6/29358)}
- A61B 2090/306: {using optical fibres}
- A61B 2576/00: Medical imaging apparatus involving image processing or analysis (A61B1/00009, A61B6/52 and A61B8/52 take precedence)
- A61B: DIAGNOSIS; SURGERY; IDENTIFICATION (usefulness limited to only animals A61D)
- G01H: MEASUREMENT OF MECHANICAL VIBRATIONS OR ULTRASONIC, SONIC OR INFRASONIC WAVES
- G02B: OPTICAL ELEMENTS, SYSTEMS OR APPARATUS

## Abstract

Techniques for imaging are disclosed. In one example, the disclosure is directed to a sensor positioned on an elongate optical fiber. The sensor comprises a plurality of blazed Bragg gratings configured to generate acoustic energy for imaging a region in response to a first optical signal, an interferometer configured to sense acoustic energy from the region and to provide a responsive second optical signal, the interferometer including a first fiber Bragg grating (FBG) and a second FBG, wherein the plurality of blazed Bragg gratings are positioned between the first and second FBGs.

## Claims

### Claim 1

A method comprising:
tuning a transmit laser to a first wavelength and transmitting first optical signals toward first blazed Bragg gratings configured to generate acoustic energies for imaging first regions in response to the first optical signals;
tracking a position of a point on a slope of a transmission notch generated within a reflection band by a pair of fiber Bragg gratings, wherein the first blazed Bragg gratings are positioned between the pair of fiber Bragg gratings; and
adjusting an operating characteristic of the transmit laser using a change in the position of the point to compensate for a change in temperature.

### Claim 2 (depends on 1)

The method of claim 1, further comprising:
sensing acoustic energies from the first regions and generating responsive optical signals;
acquiring information from the responsive optical signals.

### Claim 3 (depends on 2)

The method of claim 2, wherein the responsive optical signals are first responsive optical signals, the method further comprising:
tuning the transmit laser to a second wavelength and transmitting second optical signals toward second blazed Bragg gratings configured to generate acoustic energies for imaging second regions in response to the second optical signals;
sensing acoustic energies from the second regions and generating second responsive optical signals;
acquiring information from the second responsive optical signals; and
generating an image of the first and second regions from the information from the first and second responsive optical signals, respectively.

### Claim 4 (depends on 3)

The method of claim 3, wherein the first blazed Bragg gratings are located on a first one of a plurality of optical fibers, and wherein transmitting second optical signals toward second blazed Bragg gratings includes:
switching the second optical signals from the transmit laser to at east a second one of the plurality of optical fibers toward the second blazed Bragg gratings.

### Claim 5 (depends on 2)

The method of claim 2, wherein the first blazed Bragg gratings are located on a first one of a plurality of optical fibers, and wherein sensing acoustic energies from the first regions and generating responsive optical signals includes:
transmitting, using a receive laser, a third optical signal on another one of the optical fibers, the third optical signal to be modulated by the acoustic energies to produce the responsive optical signals, the method further comprising:
prior to generating the image, Obtaining first phase noise information from the receive laser during a first duration and second phase noise information from the receive laser during a second duration; and
subtracting the second phase noise information from the first phase noise information to improve a signal-to-noise ratio (SNR).

### Claim 6 (depends on 1)

The method of claim 1, further comprising:
displaying the generated image on a display.

### Claim 7 (depends on 1)

The method of claim 1, further comprising:
prior to generating the image, generating different polarization states to mitigate an effect of at least one of optical birefringence and ultrasound induced birefringence.

### Claim 8

A system for generating images of a body lumen, the system comprising:
a transmit laser configured to transmit first optical signals at a first wavelength toward first blazed Bragg gratings configured to generate acoustic energies for imaging first regions in response to the first optical signals;
a laser tracking circuit configured to track a position of a point on a slope of a transmission notch generated within a reflection band by a pair of fiber Bragg gratings; wherein the first blazed Bragg gratings are positioned between the pair of fiber Bragg gratings; and
a controller configured to:
tune the transmit laser to the first wavelength; and
adjust an operating characteristic of the transmit laser using a change in the position of the point to compensate for a change in temperature.

### Claim 9 (depends on 8)

The system of claim 8, further comprising:
an optical switch circuit configured to switch the first optical signals from the transmit laser to at least a first one of a plurality of optical fibers toward the first blazed Bragg gratings.

### Claim 10 (depends on 8)

The system of claim 8, wherein the first blazed Bragg gratings are located on a first one of a plurality of optical fibers, the system further comprising:
receive laser circuitry including:
a receive laser configured to transmit second optical signals at a second wavelength on a second one of the plurality of optical fibers, the second optical signals to be modulated by the acoustic energies;
data acquisition circuitry configured to acquire information from the modulated second optical signals; and
an imaging processing system configured to execute instructions that define an imaging algorithm to generate an image of the first region of the body lumen from the acquired information.

### Claim 11 (depends on 10)

The system of claim 10, further comprising:
a polarization controller configured to generate different polarization states to mitigate an effect of at least one of optical birefringence and ultrasound induced birefringence.

### Claim 12 (depends on 10)

The system of claim 10, wherein the controller is further configured to:
obtain first phase noise information from the receive laser during a first duration and second phase noise information from the receive laser during a second duration; and
subtract the second phase noise information from the first phase noise information to improve a signal-to-noise ratio (SNR).

### Claim 13 (depends on 10)

The system of claim 10, further comprising:
opto-electronics circuitry including a transmit/receive multiplexer configured to combine two different wavelengths of the transmit laser and the receive laser onto a single optical fiber.

### Claim 14 (depends on 10)

The system of claim 10, wherein the transmit laser and the receive laser circuitry form part of an optical front end, and wherein the first blazed Bragg gratings and the pair of fiber Bragg gratings form part of an imaging guidewire, the system further comprising:
a connector configured to couple the optical front end to the imaging guidewire.

### Claim 15 (depends on 14)

The system of claim 14, wherein the connector is a multi-fiber optical connector.

### Claim 16 (depends on 10)

The system of claim 10, wherein the imaging processing system includes a 3D graphics processor configured to generate 3D images from information generated by the imaging algorithm.

### Claim 17 (depends on 8)

The system of claim 8, wherein the first blazed Bragg gratings and the pair of fiber Bragg gratings form part of an imaging guidewire, wherein the imaging guidewire includes second blazed Bragg gratings, and wherein the first and second blazed Bragg gratings are tuned to different wavelengths.

### Claim 18 (depends on 8)

The system of claim 8, further comprising:
an optical switch circuit configured to switch the first optical signals from the transmit laser to at least a first one of a plurality of optical fibers toward the first blazed Bragg gratings;
receive laser circuitry including:
a receive laser coupled to a first input of the optical switch circuit and configured to transmit second optical signals at a second wavelength on a second one of the plurality of optical fibers, the second optical signals to be modulated by the acoustic energies; and
an optical delay line coupled to the receive laser and a second input of the optical switch circuit.

### Claim 19

A system for generating images of a body lumen, the system comprising:
a transmit laser configured to transmit first optical signals at a first wavelength toward first blazed Bragg gratings configured to generate acoustic energies for imaging first regions in response to the first optical signals;
a laser tracking circuit configured to track a position of a point on a slope of a transmission notch generated within a reflection band by a pair of fiber Bragg gratings, wherein the first blazed Bragg gratings are positioned between the pair of fiber Bragg gratings; and
a receive laser configured to transmit second optical signals at a second wavelength on a second one of the plurality of optical fibers, the second optical signals to be modulated by the acoustic energies;
a controller configured to:
tune the transmit laser to the first wavelength;
tune the receive laser to the second wavelength; and
adjust an operating characteristic of the transmit laser using a change in the position of the point to compensate for a change in temperature;
data acquisition circuitry configured to acquire information from the modulated second optical signals; and
an imaging processing system configured to execute instructions that define an imaging algorithm to generate an image of the first region of the body lumen from the acquired information.

### Claim 20 (depends on 19)

The system of claim 19, wherein the first blazed Bragg gratings and the pair of fiber Bragg gratings form part of an imaging guidewire, wherein the imaging guidewire includes second blazed Bragg gratings, and wherein the first and second blazed Bragg gratings are tuned to different wavelengths.
