Production of cannabinoids in yeast

A method for making Cannabigerovarinic Acid in S. cerevisiae, the method comprising:

• converting glucose to malonyl-CoA with a first nucleotide sequence comprising the nucleotide sequence of SEQ. ID. NO.124 expressing Meningitis associated and temperature regulated Fimbria (MatB);
• converting malonyl-CoA to Acetoacetyl-CoA with a second nucleotide sequence comprising the nucleotide sequence of SEQ. ID. NO.118 expressing Monocarboxylate Transporter 1 (MCT1);
• converting Acetoacetyl-CoA to 3-Hydroxybutyryl-CoA with a third nucleotide sequence comprising the nucleotide sequence of SEQ. ID. NO. 119 expressing 3-hydroxybutyryl-CoA dehydrogenase (Hbd);
• converting 3-Hydroxybutyryl-CoA to Crotonyl-CoA with a fourth nucleotide sequence comprising the nucleotide sequence of SEQ. ID. NO. 120 expressing crotonase (Crt);
• converting Crotonyl-CoA to Butyryl-CoA with a fifth nucleotide sequence comprising the nucleotide sequence of SEQ. ID. NO.123 expressing trans-enoyl-CoA reducatase (Ter);
• converting Butyryl-CoA to divarinic acid with a sixth nucleotide sequence comprising the nucleotide sequence of SEQ. ID. NO. 60 expressing Polyketide synthase and with a seventh nucleotide sequence of SEQ. ID. NO. 92 or SEQ. ID. NO. 93 expressing olivetolic acid cyclase;
• converting divarinic acid to Cannabigerovarinic Acid with an eighth nucleotide sequence comprising the nucleotide sequence of SEQ. ID. NO. 30 expressing an Aromatic prenyltransferase.