Double scatter simulation for improved reconstruction of positron emission tomography data
AssigneeSiemens Medical Solutions USA, Inc.
InventorsCharles C. Watson, Jicun Hu, Chuanyu Zhou
Life of this patent
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Abstract
Methods for simulating, and correcting for, doubly scattered annihilation gamma-ray photons in both time-of-flight (TOF) and non-TOF positron emission tomography scan data are disclosed.
Claims18
A method for applying scatter correction to a scan data acquired in a time-of-flight positron emission tomography (TOF PET) scanner, the method comprising:
- (A) selecting a pair of detector positions in the TOF PET scanner's detector ring;
- (B) numerically estimating the double scatter coincidence event rate of annihilation photons in the selected pair of detector positions, wherein the annihilation photons in a double scatter coincidence event are assumed to be scattered once, each photon by a different scatter point in the TOF PET scanner's image volume, during a TOF PET acquisition scan period;
- (C) selecting another pair of detector positions;
- (D) repeating step (B) wherein the selected pair of detector positions is the another pair of detector positions;
- (E) repeating steps (C) and (D) until all detector pairs of interest have been selected;
- and
- (F) scatter correcting the acquired scan data obtained from the pair of detector positions during the TOF PET acquisition scan period to reconstruct a TOF PET image based on the scan data.
A method for applying scatter correction to a scan data acquired in a time-of-flight positron emission tomography (TOF PET) scanner, the method comprising:
- (A) selecting a pair of detector positions in the TOF PET scanner's detector ring;
- (B) numerically estimating the double scatter coincidence event rate of annihilation photons in the selected pair of detector positions, wherein one of the pair of annihilation photons in a double scatter coincidence event is assumed not to be scattered and the other of the two photons is scattered twice by a scatter point in the TOF PET scanner's image volume, during a TOF PET acquisition scan period;
- (C) selecting another pair of detector positions;
- (D) repeating step (B) wherein the pair of detector positions is the another pair of detector positions;
- (E) repeating steps (C) and (D) until all detector pairs of interest have been selected;
- and
- (F) scatter correcting the acquired scan data obtained from the pair of detector positions during the TOF PET acquisition scan period to reconstruct a TOF PET image based on the scan data.
A system for processing and reconstructing time-of-flight positron emission tomography (TOF PET) sinogram data, comprising:
- a processor capable of executing instructions;
- and
- a non-transitory, machine readable storage medium encoded with program instructions for controlling a TOF PET scanner, such that when the processor executes the program instructions, the processor performs a method for applying scatter correction to a scan data acquired in the TOF PET scanner, the method comprising:
- (A) selecting a pair of detector positions in the TOF PET scanner's detector ring;
- (B) numerically estimating the double scatter coincidence event rate of annihilation photons in the selected pair of detector positions, wherein the annihilation photons in a double scatter coincidence event are assumed to be scattered once, each photon by a different scatter point in the TOF PET scanner's image volume, during a TOF PET acquisition scan period;
- and
- (C) selecting another pair of detector positions;
- (D) repeating step (B) wherein the selected pair of detector positions is the another pair of detector positions;
- (E) repeating steps (C) and (D) until all detector pairs of interest have been selected;
- and
- (F) scatter correcting the acquired scan data obtained from the pair of detector positions during the TOF PET acquisition scan period to reconstruct a TOF PET image based on the scan data.
A non-transitory, machine readable storage medium encoded with program instructions for controlling a time-of-flight positron emission tomography (TOF PET) scanner, such that when a processor executes the program instructions, the processor performs a method for applying scatter correction to a scan data acquired in the TOF PET scanner, the method comprising:
- (A) selecting a pair of detector positions in the TOF PET scanner's detector ring;
- (B) numerically estimating the double scatter coincidence event rate of annihilation photons in the selected pair of detector positions, wherein the annihilation photons in a double scatter coincidence event are assumed to be scattered once, each photon by a different scatter point in the TOF PET scanner's image volume, during a TOF PET acquisition scan period;
- and
- (C) selecting another pair of detector positions;
- (D) repeating step (B) wherein the selected pair of detector positions is the another pair of detector positions;
- (E) repeating steps (C) and (D) until all detector pairs of interest have been selected;
- and
- (F) scatter correcting the acquired scan data obtained from the pair of detector positions during the TOF PET acquisition scan period to reconstruct a TOF PET image based on the scan data.
A system for processing and reconstructing time-of-flight positron emission tomography (TOF PET) sinogram data, comprising:
- a processor capable of executing instructions;
- and
- a non-transitory, machine readable storage medium encoded with program instructions for controlling a TOF PET scanner, such that when the processor executes the program instructions, the processor performs a method for applying scatter correction to a scan data acquired in the TOF PET scanner, the method comprising:
- (A) selecting a pair of detector positions in the TOF PET scanner's detector ring;
- (B) numerically estimating the double scatter coincidence event rate of annihilation photons in the selected pair of detector positions, wherein one of the pair of annihilation photons in a double scatter coincidence event is assumed not to be scattered and the other of the two photons is scattered twice by a scatter point in the TOF PET scanner's image volume, during a TOF PET acquisition scan period;
- (C) selecting another pair of detector positions;
- (D) repeating step (B) wherein the pair of detector positions is the another pair of detector positions;
- (E) repeating steps (C) and (D) until all detector pairs of interest have been selected;
- and
- (F) scatter correcting the acquired scan data obtained from the pair of detector positions during the TOF PET acquisition scan period to reconstruct a TOF PET image based on the scan data.
A non-transitory, machine readable storage medium encoded with program instructions for controlling a time-of-flight positron emission tomography (TOF PET) scanner, such that when a processor executes the program instructions, the processor performs a method for applying scatter correction to a scan data acquired in the TOF PET scanner, the method comprising:
- (A) selecting a pair of detector positions in the TOF PET scanner's detector ring;
- (B) numerically estimating the double scatter coincidence event rate of annihilation photons in the selected pair of detector positions, wherein one of the pair of annihilation photons in a double scatter coincidence event is assumed not to be scattered and the other of the two photons is scattered twice by a scatter point in the TOF PET scanner's image volume, during a TOF PET acquisition scan period;
- (C) selecting another pair of detector positions;
- (D) repeating step (B) wherein the pair of detector positions is the another pair of detector positions;
- (E) repeating steps (C) and (D) until all detector pairs of interest have been selected;
- and
- (F) scatter correcting the acquired scan data obtained from the pair of detector positions during the TOF PET acquisition scan period to reconstruct a TOF PET image based on the scan data.
Dependencies are inferred from the claim text.