Method and apparatus for quantifying solutions comprised of multiple analytes
AssigneeFinesse Solutions, Inc.
InventorsMark Selker, Barbara Paldus
Life of this patent
Estimating the term…
Abstract
A multi-analyte sensor system based on hollow core photonic bandgap fiber and Raman anti-Stokes spectroscopy. The system includes: i) an inlet to introduce an analyte sample into an analyzer chamber which analyzer includes; ii) a measurement system to derive the anti-Stokes spectral peaks and/or spectra of the sample; iii) a set of reference calibrants corresponding to the analytes of which the sample is primarily comprised; iv) a second inlet to introduce said calibrants into the analyzer chamber; v) a second measurement system to derive the anti-Stokes spectral peaks and/or spectra of the calibrants vi) an outlet through which the sample and calibrants are expelled from the analyzer chamber.
Claims20
An analyzer system for determining the identity and concentration of at least one target analyte present in a gaseous or liquid sample utilizing the Raman optical scattering effect, the analyzer system comprising:
- (i) a laser light source emitting light which generates Raman Stokes and anti-Stokes emissions when incident on the target analyte;
- (ii) one or more hollow core photonic band-gap (HCPBG) fibers optically connected to the laser light source, HCPBG fibers including:
- (a) a first inlet permitting introduction of a sample containing the target analyte into the HCPBG fibers;
- and
- (b) at least one reference calibrant in the HCPBG fibers, the reference calibrant corresponding to an analyte in the sample;
- (iii) a pump configured to inject the sample containing the target analyte into the core of the HCPBG fiber;
- and
- (iv) a spectral analysis system optically coupled to the HCPBG fibers and configured to derive the Raman anti-Stokes spectral peaks and/or spectra of the reference calibrant to establish a baseline response and account for cross sensitivities or spectral peak overlaps in the sample.
A system for the determination of the concentration of at least one target analyte present in a gaseous or liquid sample using Raman anti-Stokes radiation spectroscopy the system comprising:
- (a) a laser pump light source;
- (b) an inlet for the laser pump light source into one or more hollow core photonic band gap (HCPBG) fibers, the HCPBG fibers operating in a fundamental mode or a limited number of modes, the HCPBG fibers configured to contain a reference calibrant;
- (c) a pump configured to introduce the sample containing the at least one target analyte into the core of the HCPBG fiber via an inlet port;
- (d) a spectral analysis system comprising at least one filter and/or dispersive element and a detector array or CCD including means for detecting and quantifying Raman anti-Stokes spectrum and/or spectral peaks emitted by the reference calibrant to establish a baseline response and account for cross sensitivities or spectral peak overlaps in the sample when illuminated by the laser pump light source;
- (e) means for optically coupling components (a) and (d) to the core of the HCPBG fiber.
A method of determining the identity and concentration of at least one target analyte present in a gaseous or liquid sample utilizing the Raman optical scattering effect, the method comprising:
- exciting a reference calibrant in one or more hollow core photonic band-gap (HCPBG) fibers, using an excitation light source, the reference calibrant corresponding to a target analyte in a sample;
- as a result of exciting the at least one reference calibrant, deriving the Raman anti-Stokes spectral peaks and/or spectra of the reference calibrant to establish a baseline response, using a spectral analysis system optically coupled to the HCPBG fibers;
- introducing the sample containing the target analyte into the one or more HCPBG fibers though an inlet in fluid communication with a hollow core of the HCPBG fibers;
- exciting the sample using the excitation light source;
- as a result of exciting the sample containing the target analyte, deriving the Raman anti-Stokes spectral peaks and/or spectra of the target analyte from the Raman anti-Stokes light received and accounting for cross sensitivities or spectral peak overlaps in the sample containing the target analyte;
- and
- expelling the sample containing the target analyte from the hollow core of the HCPBG fibers.
Dependencies are inferred from the claim text.