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US 11,266,712 B2Granted
Antimicrobial peptides and methods of using the same
AssigneeRiptide Bioscience, Inc.
InventorsJesse M. Jaynes, L. Edward Clemens, Henry Wilfred Lopez, George R. Martin, Kathryn Woodburn
Life of this patent
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Abstract
Aspects of the present invention relate to peptides having antimicrobial activity. In certain aspects, the invention relates to peptides having potent antimicrobial activity, broad-spectrum antimicrobial activity, and/or the ability to kill otherwise antibiotic-resistant microbes, or microbes protected by biofilms.
Claims24
A peptide, comprising:
- a) a peptide sequence selected from RP550-557 (SEQ ID NO:
- 1 to SEQ ID NO:
- 8), RP559-562 (SEQ ID NO:
- 10 to SEQ ID NO:
- 13), RP566 (SEQ ID NO:
- 17) or RP567 (SEQ ID NO:
- 18);
- b) a sequence having at least 90% sequence identity with the sequence defined in a);
- or
- c) a sequence having three or less amino acid substitutions relative to the sequence defined in a), wherein the three or less amino acid substitutions are conservative amino acid substitutions according to Table 3.
7 more elements
Dependencies are inferred from the claim text.