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US 11,266,337 B2Granted
Systems, methods, and devices for sample collection, stabilization and preservation
AssigneeDrawbridge Health, Inc.
InventorsAlicia Jackson, Rowan Chapman, Diana Maichin, Harry Glorikian
Life of this patent
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Abstract
Herein, systems and methods are disclosed including a sample acquisition component (SAC) for user-friendly sample collection, a separation component for optional separation of plasma, and one or more stabilization components for stabilizing analytes. In a particular embodiment, the system and methods are directed towards sample collection and stabilization with optional sample separation. Other embodiments can perform any combination of collection, separation, stabilization or detection.
Claims20
A method for collecting a bio-sample from a subject, the method comprising
- obtaining an integrated sample acquisition and sample stabilization device comprising:
- (i) a sample acquisition component, wherein the sample acquisition component comprises piercing elements;
- and (ii) more than one paper stabilization matrix, wherein the more than one paper stabilization matrices are stacked and do not contact each other;
- wherein the more than one paper stabilization matrices are separated by one or more solid supports wherein the one or more solid supports do not comprise filters;
- applying the device to a skin of the subject;
- actuating the sample acquisition component causing the piercing elements to puncture the skin of the subject;
- withdrawing the piercing elements under vacuum, causing the bio-sample to enter an opening in the sample acquisition component;
- and
- moving the bio-sample from the opening in the sample acquisition component through a channel onto the more than one paper stabilization matrices that are stacked and do not contact each other, wherein the bio-sample is collected on the more than one paper stabilization matrices, wherein during the moving, the more than one paper stabilization matrices are stacked and do not contact each other,
- wherein the moving the bio-sample from the opening in the sample acquisition component through the channel onto the more than one paper stabilization matrices that are stacked and do not contact each other occurs by vacuum.
7 more elements
Dependencies are inferred from the claim text.