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US 11,261,216 B2Granted
Engineered hepatitis B core polypeptide
AssigneeThe Board of Trustees of the Leland Stanford Junior University
InventorsJames R. Swartz, Rinchu Mathew, Marcus John Rohovie, Maya Nagasawa
Life of this patent
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Abstract
Genetically modified HBc polypeptides are provided.
Claims17
A hepatitis B core protein (HBc) polypeptide, comprising a hydrophobic cargo-loading domain at the carboxy terminus, wherein the cargo-loading domain is selected from EGFGEGFGEGF (SEQ ID NO:4);
- EGFGEGFGEGFC (SEQ ID NO:5);
- IGIGC (SEQ ID NO:6);
- and IGIGIC (SEQ ID NO:7).
Dependencies are inferred from the claim text.