Methods of and systems for measuring analytes using batch calibratable test strips
AssigneeBiometry Inc.
InventorsBryan Nolan, Thomas T. Morgan, David L. Carnahan
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Abstract
Systems and methods for measuring analytes in fluid samples are disclosed. The systems and methods employ test strips which are generally comprised of a substrate, at least one electrical connection, at least one sensing chemistry and at least one additional layer. The test strips can be batch calibrated.
Claims26
A method for determining the concentration of an analyte in a fluid sample, said method comprising:
- providing a system for determining the concentration of at least one analyte in a fluid sample, the system comprising:
- a base substrate;
- a first electrode pair disposed over the substrate;
- a conversion chamber adapted for producing an altered analyte by oxidizing or reducing the at least one analyte in the fluid sample;
- and
- an active sensing chemistry in electrical communication with the first electrode pair;
- wherein the active sensing chemistry is responsive to the altered analyte and wherein the active sensing chemistry forms an irreversible chemical bond with the altered analyte
- measuring at least one of a voltage across the first electrode pair, a resistance across the first electrode pair, and a current flow across the first electrode pair.
A system for determining the concentration of at least one analyte in a fluid sample, the system comprising:
- a base substrate;
- a first electrode pair disposed over the substrate;
- and
- a conversion chamber adapted for producing an altered analyte by oxidizing or reducing the at least one analyte in the fluid sample;
- and
- an active sensing chemistry in electrical communication with the first electrode pair, wherein the active sensing chemistry is responsive to the altered analyte, and wherein the active sensing chemistry forms an irreversible chemical bond with the altered analyte.
A system for determining the concentration of at least one analyte in a fluid sample, the system comprising:
- a base substrate;
- a first electrode pair disposed over the substrate;
- and
- an active sensing chemistry in electrical communication with the first electrode pair;
- wherein the active sensing chemistry is responsive to the analyte, wherein the active sensing chemistry forms an irreversible chemical bond with the analyte, and wherein the active sensing chemistry is a coffee ring shape bridging the electrode pair.
A method for determining the concentration of an analyte in a fluid sample, said method comprising:
- providing a system for determining the concentration of at least one analyte in a fluid sample, the system comprising:
- a base substrate,
- a first electrode pair disposed over the substrate, and
- an active sensing chemistry in electrical communication with the first electrode pair,
- wherein the active sensing chemistry is responsive to the analyte, wherein the active sensing chemistry forms an irreversible chemical bond with the analyte, wherein the active sensing chemistry is a coffee ring shape bridging the electrode pair;
- and
- measuring at least one of a voltage across the first electrode pair, a resistance across the first electrode pair, and a current flow across the first electrode pair.
Dependencies are inferred from the claim text.