Salivary urea nitrogen rapid detection
AssigneesDignity Health, Arizona Board of Regents on behalf of Arizona State University
InventorsAntonio Garcia, Abraham Lieberman
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Abstract
Apparatus and methods for measuring a concentration of a target molecule from a biological sample are disclosed. In one example, the apparatus includes a porous pad, which is impregnated with a solution containing at least one agent and which contains an unfilled capillary matrix, a housing for the porous pad, and a membrane that covers the porous pad.
Claims27
An apparatus comprising a porous pad for measuring a concentration of a target molecule from a biological sample,
- wherein:
- the porous pad is impregnated with a solution containing at least one agent configured to measure the concentration of the target molecule;
- the porous pad comprises an unfilled capillary matrix;
- the solution further comprises polyhydroxy organic compounds selected from the group consisting of glycerol, sucrose, polysorbate, ethylene glycol, propylene glycol, and a combination thereof;
- and
- the solution has a viscosity level higher than a viscosity of the biological sample to create viscous fingering instabilities.
A salivary urea nitrogen level testing kit comprising:
- a saliva collecting device, a porous pad, an ammonia level indicating strip, and a hydrophobic and gas permeable membrane disposed between the porous pad and the ammonia level indicating strip,
- wherein the saliva collecting device comprises a funnel configured to receive the saliva, a container in fluid communication with the funnel and configured to store the saliva, and a tray in fluid communication with the container and in fluid communication with the porous pad so that the porous pad is able to absorb the saliva.
A salivary urea nitrogen level testing kit comprising:
- a saliva collecting device, a porous pad, a gas sensor, and a hydrophobic and gas permeable membrane disposed between the porous pad and the gas sensor,
- wherein the saliva collecting device comprises a funnel configured to receive the saliva, a container in fluid communication with the funnel and configured to store the saliva, and a tray in fluid communication with the container and in fluid communication with the porous pad to have the porous pad absorb the saliva.
An apparatus comprising:
- a porous pad comprising an unfilled capillary matrix, impregnated with a solution containing at least one agent, wherein the at least one agent is configured for measuring a concentration of a target molecule from a biological sample;
- a housing upon which the porous pad is disposed;
- a hydrophobic and gas permeable membrane that covers the porous pad;
- and
- a biological sample collecting device that includes:
- a funnel dimensioned to receive the biological sample;
- a container in fluid communication with the funnel and configured to store the biological sample;
- and
- a tray in fluid communication with the container and in fluid communication with the porous pad.
Dependencies are inferred from the claim text.