Beta-hydroxybutyrate mixed salt compositions and methods of use
AssigneeAxcess Global Sciences, LLC
InventorGary Millet
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Abstract
Ketogenic compositions including a plurality of beta-hydroxybutyrate (BHB) salts are formulated to induce or sustain ketosis in a subject to which the ketogenic compositions are administered. The BHB mixed salt is formulated to provide a biologically balanced set of cationic electrolytes and avoid detrimental health effects associated with imbalanced electrolyte ratios. A ketogenic composition includes BHB salts selected from sodium, potassium, calcium, and magnesium salts. The BHB composition may also include transition metal cations (e.g., zinc or iron), one or more BHB-amino acid salts, a short-, medium-, or long-chain fatty acid source, vitamins, minerals, flavorants, or other excipients.
Claims20
A composition for increasing ketone level in a subject, comprising:
- a plurality of beta-hydroxybutyrate salts comprised of:
- at least one beta-hydroxybutyrate salt selected from:
- calcium beta-hydroxybutyrate;
- and
- magnesium beta-hydroxybutyrate;
- and
- at least one other beta-hydroxybutyrate salt selected from:
- sodium beta-hydroxybutyrate;
- potassium beta-hydroxybutyrate;
- calcium beta-hydroxybutyrate;
- magnesium beta-hydroxybutyrate;
- and
- amino acid salts of beta-hydroxybutyrate,
- wherein the beta-hydroxybutyrate salts comprise at least 20% by total weight of calcium beta-hydroxybutyrate and/or magnesium beta-hydroxybutyrate,
- wherein the composition is in solid and/or powder form,
- wherein the composition is free of medium chain fatty acids having 6 to 12 carbons and glycerides or other esters thereof.
A composition for increasing ketone level in a subject, comprising:
- at least one beta-hydroxybutyrate salt selected from:
- calcium beta-hydroxybutyrate;
- and
- magnesium beta-hydroxybutyrate;
- and
- at least one other beta-hydroxybutyrate salt selected from:
- sodium beta-hydroxybutyrate;
- potassium beta-hydroxybutyrate;
- calcium beta-hydroxybutyrate;
- magnesium beta-hydroxybutyrate;
- and
- amino acid salts of beta-hydroxybutyrate,
- wherein the composition comprises a greater total weight of calcium and magnesium beta-hydroxybutyrate salts than a total weight of sodium and potassium beta-hydroxybutyrate salts,
- wherein the composition is free of medium chain fatty acids having 6 to 12 carbons and glycerides or other esters thereof.
A composition for increasing ketone level in a subject, comprising:
- a plurality of beta-hydroxybutyrate salts comprised of:
- at least one beta-hydroxybutyrate salt selected from:
- calcium beta-hydroxybutyrate;
- and
- magnesium beta-hydroxybutyrate;
- and
- at least one other beta-hydroxybutyrate salt selected from:
- sodium beta-hydroxybutyrate;
- potassium beta-hydroxybutyrate;
- calcium beta-hydroxybutyrate;
- magnesium beta-hydroxybutyrate;
- and
- amino acid salts of beta-hydroxybutyrate,
- wherein the beta-hydroxybutyrate salts comprise at least 15% and less than 50% by total weight of calcium and magnesium beta-hydroxybutyrate salts,
- wherein the composition comprises a greater total weight of sodium and potassium beta-hydroxybutyrate salts than a total weight of calcium and magnesium beta-hydroxybutyrate salts,
- wherein the composition is free of medium chain fatty acids having 6 to 12 carbons and glycerides or other esters thereof.
A composition for increasing ketone level in a subject, comprising:
- a plurality of beta-hydroxybutyrate salts comprised of:
- at least one beta-hydroxybutyrate salt selected from:
- calcium beta-hydroxybutyrate;
- and
- magnesium beta-hydroxybutyrate;
- and
- at least one other beta-hydroxybutyrate salt selected from:
- sodium beta-hydroxybutyrate;
- potassium beta-hydroxybutyrate;
- calcium beta-hydroxybutyrate;
- magnesium beta-hydroxybutyrate;
- and
- amino acid salts of beta-hydroxybutyrate,
- wherein the beta-hydroxybutyrate salts comprise at least 20% by total weight of calcium beta-hydroxybutyrate and/or magnesium beta-hydroxybutyrate;
- and
- at least one of anticaking agent, flow agent, moisture absorber, aluminosilicate, ferrocyanide, silicate, phosphate, or powdered cellulose,
- wherein the composition is free of medium chain fatty acids having 6 to 12 carbons and glycerides or other esters thereof.
Dependencies are inferred from the claim text.