Device and method of handling transmission/reception for serving cell

A communication device for handling transmission/reception for a serving cell, comprising:

• a storage unit, for storing instructions of:
• receiving an indication indicating at least one physical resource block (PRB) group of a plurality of PRB groups of a serving cell from a network, wherein at least one location and at least one bandwidth of the at least one PRB group are configured by a higher layer signaling transmitted by the network;
• and
• performing a communication operation in the at least one PRB group with the network, after receiving the indication;
• wherein each of the plurality of PRB groups comprises at least one physical uplink (UL) control channel (PUCCH) resource;
• wherein each of the at least one PUCCH resource indicates a starting symbol index and a duration of a PUCCH;
• wherein the communication operation comprises transmitting a UCI and a demodulation reference signal (DMRS) with a PUCCH format in a PUCCH and a physical UL shared channel (PUSCH) in one of the at least one PRB group, the PUCCH and the PUSCH are transmitted according to a time-division multiplexing (TDM) scheme, and the PUCCH is transmitted according a code-division multiplexing (CDM) scheme;
• and
• a processing circuit, coupled to the storage unit, configured to execute the instructions stored in the storage unit.