Personalizing selection of digital programs for patients in decentralized clinical trials and other health research

A method of selectively distributing programs to remote devices based on monitoring performed by the remote devices, the method being performed by a server system comprising one or more computers configured to monitor incoming data received from the remote devices over a communication network to determine changes to programs for the remote devices, the method comprising:

• storing, by the server system, a database of program data for each of a plurality of programs that involve monitoring using remote devices,
• the program data comprising, for each of the programs,
• (i) a program profile indicating characteristics of the program, and
• (ii) configuration data for configuring a remote device to carry out monitoring for the program;
• distributing, by the server system, program data for the programs to remote devices over a communication network;
• generating, by the server system, first scores for the programs for each of the respective remote devices, wherein the first scores each indicate a degree of relevance of a program with respect to a remote device;
• providing, by the server system, configuration data to the respective remote devices over the communication network, wherein the configuration data enables programs for monitoring that were selected for the respective remote devices based at least in part on the first scores;
• collecting, by the server system and from the respective remote devices, monitoring data that is generated by the programs respectively enabled for the remote devices and is provided over the communication network;
• after collecting the monitoring data from the remote devices, generating, by the server system, second scores for the programs that are respectively enabled for the respective remote devices, the second scores indicating updated degrees of relevance of the enabled programs with respect to the remote devices based on the monitoring data, wherein, for each of at least some of remote devices with enabled programs, the second score for an enabled program with respect to a remote device indicates lower relevance than the first score for the enabled program with respect to the remote device;
• identifying, by the server system and based on the second scores, a subset of the remote devices for which a program change is recommended, the subset including at least some remote devices for which the enabled programs have decreased in relevance or in ranking with respect to the other programs;
• selecting, by the server system, one or more program changes for the remote devices in the subset based on the program profiles in the database, the monitoring data collected by the remote devices in the subset, and the second scores for the programs;
• and
• based at least in part on the selected one or more program changes, causing, by the server system the remote devices in the subset to change the sets of programs that are respectively enabled at the remote devices, wherein the server system provides data to each of the remote devices in the subset to cause the remote device to (i) disable a program or (ii) enable a program that was not enabled.

At least one non-transitory computer-readable storage device storing instructions that, when executed by one or more processors, cause the one or more processors to perform operations comprising:

• storing, by the server system, a database of program data for each of a plurality of programs that involve monitoring using remote devices,
• the program data comprising, for each of the programs,
• (i) a program profile indicating characteristics of the program, and
• (ii) configuration data for configuring a remote device to carry out monitoring for the program;
• distributing, by the server system, program data for the programs to remote devices over a communication network;
• generating, by the server system, first scores for the programs for each of the respective remote devices, wherein the first scores each indicate a degree of relevance of a program with respect to a remote device;
• providing, by the server system, configuration data to the respective remote devices over the communication network, wherein the configuration data enables programs for monitoring that were selected for the respective remote devices based at least in part on the first scores;
• collecting, by the server system and from the respective remote devices, monitoring data that is generated by the programs respectively enabled for the remote devices and is provided over the communication network;
• after collecting the monitoring data from the remote devices, generating, by the server system, second scores for the programs that are respectively enabled for the respective remote devices, the second scores indicating updated degrees of relevance of the enabled programs with respect to the remote devices based on the monitoring data, wherein, for each of at least some of remote devices with enabled programs, the second score for an enabled program with respect to a remote device indicates lower relevance than the first score for the enabled program with respect to the remote device;
• identifying, by the server system and based on the second scores, a subset of the remote devices for which a program change is recommended, the subset including at least some remote devices for which the enabled programs have decreased in relevance or in ranking with respect to the other programs;
• selecting, by the server system, one or more program changes for the remote devices in the subset based on the program profiles in the database, the monitoring data collected by the remote devices in the subset, and the second scores for the programs;
• and
• based at least in part on the selected one or more program changes, causing, by the server system the remote devices in the subset to change the sets of programs that are respectively enabled at the remote devices, wherein the server system provides data to each of the remote devices in the subset to cause the remote device to (i) disable a program or (ii) enable a program that was not enabled.