Inductively coupled plasma mass spectrometer with mass correction
AssigneeAgilent Technologies, Inc.
InventorsNaoki Sugiyama, Amir Liba, Mark Lee Kelinske, Glenn David Woods
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Abstract
Systems and methods for controlling mass filtering of polyatomic ions in an ion beam passing through an inductively coupled plasma mass spectrometer (ICP-MS). Polyatomic ion mass data representative of the exact mass of a polyatomic ion having a target isotope is determined. A control signal is generated based on the determined polyatomic ion mass data and output to an ICP-MS to filter based on mass the polyatomic ions in the ion beam traveling through the ICP-MS to an ion detector.
Claims20
A method for controlling mass filtering of polyatomic ions in an ion beam passing through an inductively coupled plasma mass spectrometer (ICP-MS), the method comprising:
- determining polyatomic ion mass data representative of the exact mass of a polyatomic ion having a target isotope, wherein the exact mass is based on the target isotope and a cell gas used in the ICP-MS to form the polyatomic ions in the ion beam;
- generating a first control signal based on the determined polyatomic ion mass data;
- and
- outputting the first control signal to an ICP-MS to filter based on mass the polyatomic ions in the ion beam traveling through the ICP-MS to an ion detector.
An element analyzer system configurable for use in an inductively coupled plasma mass spectrometer (ICP-MS), comprising:
- a user-interface that enables a user to input selections for analyzing a target isotope included in a polyatomic ion;
- and
- one or more processors coupled to the user-interface and configured to received data representative of the input selections and further configured to:
- determine polyatomic ion mass data representative of the exact mass of a polyatomic ion having a target isotope, wherein the exact mass is based on the target isotope and a cell gas used in the ICP-MS to form the polyatomic ions in the ion beam;
- generate a first control signal based on the determined polyatomic ion mass data;
- and
- initiate output of the first control signal to an ICP-MS to filter based on mass the polyatomic ions in the ion beam traveling through the ICP-MS.
An element analyzer system comprising:
- an inductively coupled plasma mass spectrometer;
- a workstation coupled to the inductively coupled plasma mass spectrometer, wherein the workstation includes:
- a user-interface that enables a user to input selections for analyzing a target element isotope included in a polyatomic ion;
- and
- one or more processors coupled to the user-interface and configured to received data representative of the input selections and further configured to:
- determine a first exact mass (EM1) of the target element isotope;
- evaluate whether a mass deviation correction is needed for the elemental analysis of the target element isotope included in the polyatomic ion;
- and
- when mass deviation correction is needed, determine a second exact mass (EM2) of the target elemental isotope as a function of a mass number corresponding to the target polyatomic ion and a mass deviation correction corresponding to a reactant in the reaction cell.
Dependencies are inferred from the claim text.