A process cartridge that integrally supports an electrophotographic photosensitive member including a cylindrical support, a charge generating layer and a charge transport layer in this order, and at least one unit selected from the group consisting of a charging unit, a developing unit and a cleaning unit, and is detachably attachable to a body of an electrophotographic apparatus,
- the charge generating layer co comprising titanyl phthalocyanine crystals as a charge generating substance, said titanyl phthalocyanine crystals having a strong peak at a Bragg angle 2θ of 27.2°±0.3° in CuKα characteristic X-ray diffraction, wherein
- d1<d2<d3<d4<d5 and D1<D2<D3<D4<D5 when a region from a central position of an image formation region of the electrophotographic photosensitive member to an end position of the image formation region in an axial direction of the cylindrical support is equally divided into live regions, d1, d2, d3, d4 and d5 are average film thicknesses (nm) of the charge generating layer in the five regions and D1, D2, D3, D4 and D5 are average film thicknesses (μm) of the charge transport layer in the five regions.