Biological analysis devices and systems

A biological analysis system comprising:

• an excitation module comprising:
• an excitation light source configured to emit excitation light in a first direction;
• an excitation mirror selectively movable between a plurality of predefined positions, each predefined position forming an acute angles relative to the first direction and being configured to reflect the excitation light along a second direction;
• and
• a plurality of excitation lenses arrayed such that each excitation lens is positioned in the second direction and is configured to receive a reflected beam of excitation light directed thereto by the excitation mirror positioned in a respective predefined position;
• and
• an emission module comprising:
• a plurality of sample receptacles positioned to receive focused beams of reflected excitation light from the corresponding plurality of excitation lenses;
• and
• at least one photodetector configured to receive emission light transmitted in a third direction from the plurality of sample receptacles, the third direction being transverse to the second direction;
• and
• a plurality of emission lenses and a plurality of emission filters configured to focus and filter the emission light onto the at least one photodetector.

A biological analysis system, comprising:

• at least two excitation light sources emitting different excitation wavelengths;
• a collimator element configured to receive excitation light from the at least two excitation light sources and to transmit collimated excitation light along an excitation light path in a first direction;
• a plurality of excitation mirrors arrayed in a staggered, diagonal pattern along the excitation light path, wherein each excitation mirror is disposed at an acute angle relative to the first direction and configured to reflect a respective beam of collimated excitation light along a second direction of the excitation light path;
• a plurality of excitation lenses positioned in the second direction of the excitation light path and is configured to focus respective, reflected beam of collimated light into corresponding focused beams of excitation light;
• a sample block forming a plurality of sample receptacles, wherein the plurality of sample receptacles are positioned to receive the corresponding focused beams of excitation light;
• and
• for each respective sample receptacle, the biological analysis system comprises at least the following components aligned in a third direction, the third direction being transverse to the second direction:
• an emission window defining an area through which emission light is transmitted in the third direction;
• a curved lens configured to focus the emission light passing through the emission window;
• a dual bandpass filter configured to substantially block stray excitation light;
• and
• a photodetector configured to receive the focused, filtered emission light.

A biological analysis system comprising:

• an excitation module, comprising:
• a collimator element configured to receive excitation light from at least one excitation light source and to transmit collimated excitation light along an excitation light path in a first direction;
• and
• a plurality of excitation mirrors arrayed along the excitation light path, wherein each excitation mirror is disposed at an acute angle relative to the first direction and configured to reflect a respective beam of collimated excitation light along a second direction of the excitation light path;
• and
• an emission module positioned to receive excitation light transmitted along the second direction of the excitation light path, the emission module comprising:
• a sample block comprising a plurality of sample receptacles, each sample receptacle positioned to receive a respective beam of collimated excitation light transmitted along the second direction of the excitation light path;
• a plurality of photodetectors, each photodetector configured to receive emission light transmitted in a third direction from a respective sample receptacle, the third direction being transverse to the second direction of the excitation light path;
• and
• a plurality of emission lenses configured to focus emission light transmitted in the third direction onto the plurality of photo detectors.

A biological analysis system comprising:

• an excitation module, comprising:
• a collimator element configured to receive excitation light from at least one excitation light source and to transmit collimated excitation light along an excitation light path in a first direction;
• a plurality of excitation mirrors arrayed along the excitation light path, wherein each excitation mirror is disposed at an acute angle relative to the first direction and configured to reflect a respective beam of collimated excitation light along a second direction of the excitation light path, wherein the plurality of excitation mirrors are arrayed in a staggered, diagonal pattern formed by a first center point of a first excitation lens being offset vertically and horizontally from a second center point of a second excitation lens, and the acute angle of each excitation mirror in the staggered, diagonal pattern is between 50° and 75° relative to the first direction;
• and
• an emission module positioned to receive excitation light transmitted along the second direction of the excitation light path, the emission module comprising:
• a sample block comprising a plurality of sample receptacles, each sample receptacle positioned to receive a respective beam of collimated excitation light transmitted along the second direction of the excitation light path;
• and
• a plurality of photodetectors, each photodetector configured to receive emission light transmitted in a third direction from a respective sample receptacle, the third direction being transverse to the second direction of the excitation light path.