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US 11,236,374 B2Granted
Modified homoserine dehydrogenase and method for producing homoserine or L-amino acid derived from homoserine using the same
AssigneeCj Cheiljedang Corporation
InventorsHyo Jin Kim, Lan Huh, Sang Jo Lim, Hyun Ah Kim, Hyoung Joon Kim, Chang il Seo, Seung Bin Lee, Ji Sun Lee
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Abstract
The present disclosure relates to modified homoserine dehydrogenase and a method for producing a homoserine-derived L-amino acid using the same.
Claims16
A modified homoserine dehydrogenase having at least 95% sequence identity with the polypeptide of SEQ ID NO:
- 1, wherein said modified homoserine dehydrogenase comprises an isoleucine at the position corresponding to position 285 of the polypeptide of SEQ ID NO:
- 1, and/or a glutamine at the position corresponding to position 398 of the polypeptide of SEQ ID NO:
- 1, and wherein the modified homoserine dehydrogenase has homoserine dehydrogenase activity.
Dependencies are inferred from the claim text.