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US 11,236,336 B2Granted
Therapeutic targeting of a microRNA to treat Duchenne muscular dystrophy
AssigneesThe General Hospital Corporation, Aalborg University
InventorsAnders M. Naar, Sakari Kauppinen, Andreas Petri
Life of this patent
Estimating the term…
Abstract
Methods of treating Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD), comprising administering an inhibitory nucleic acid that targets miR-128.
Claims29
A method of treating a subject who has Duchenne muscular dystrophy (DMD) or Becker muscular dystrophy (BMD), the method comprising administering to the subject:
- (i) a therapeutically effective amount of an inhibitory nucleic acid that is complementary to all or part of any of SEQ ID NOs:
- 1-6, and
- (ii) an additional treatment for DMD or BMD.
A pharmaceutical composition comprising an inhibitory nucleic acid that is complementary to all or part of any of SEQ ID NOs:
- 1-6, optionally which is or comprises +G*+G*+T*+T*C*A*C*+T*+G*+T*+G (SEQ ID NO:8), and an additional therapeutic for DMD or BMD.
Dependencies are inferred from the claim text.