US 11,236,137 B2Granted

Recombinant Dermatophagoides farinae type 2 allergen protein and its preparation method and application

AssigneeZonhon Biopharma Institute Inc.

InventorsBruce Yong Ma, Yu Fan, Jun Wang, Anliang Wang

Life of this patent

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Abstract

Provided are an optimized Der f2 gene, a recombinant Der f2 protein encoded thereby, a vector comprising said gene, and a Pichia pastoris strain. Also provided are an expression method, a purification method, and an application of the recombinant Der f2 protein.

Claims8

Dependent claims

A DNA sequence encoding a Der f2 protein, wherein said DNA sequence has a base sequence as shown in SEQ ID NO:

Dependencies are inferred from the claim text.

Facts

Application: 16/456,218Filed 28 Jun 2019 · continuation
Priority: CN 201611267247.531 Dec 2016
Published: US 2019/0389918 A126 Dec 2019
Granted: 1 Feb 2022
Term ends: Not estimatedThe source records don’t support an estimate.

Classification17 codes

C07K 14/43531
From arachnidae: from mites
A61K 39/35
Medicinal preparations containing antigens or antibodies: allergens
A61P 37/08
Drugs for immunological or allergic disorders: antiallergic agents
C07K 1/18
By chromatography: ion-exchange chromatography

Family

PCT/CN2017/119200Parent of this continuation · filed 28 Dec 2017
US 2019/0389918 A1Pre-grant publication · published 26 Dec 2019
US 11,236,137 B2This patent

From the US filing history. Foreign family members aren’t listed.

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