Nepovirus coat protein fusion polypeptides and their use
AssigneesInstitut National De Recherche Pour L'agriculture, L'alimentation Et L'environnement, Universite De Strasbourg, Centre National De La Recherche Scientifique
InventorsLorène Belval, Gérard Demangeat, Caroline Hemmer, Christophe Ritzenthaler
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Abstract
The present invention relates to novel fusion polypeptides and the uses thereof. The invention particularly relates to conjugated coat proteins derived from nepoviruses, virus-like particles made with such proteins, and the uses thereof. The particles of the invention can expose and/or encage molecules of interest and have utility in various fields such as the pharmaceutical, agro, or veterinary areas.
Claims11
A virus-like particle comprising a nepovirus coat protein conjugated to a compound, wherein the compound is conjugated to the C-terminus of the coat protein by ligand-mediated attachment and the nepovirus coat protein is a grapevine fanleaf virus (GFLV) coat protein.
Dependencies are inferred from the claim text.