Re-directed immunotherapy

An agent for retargeting T cells to solid tumor cells, the agent comprising:

• (i) a targeting moiety that is capable of targeting to the solid tumor cells, wherein the targeting moiety is an antibody or antigen binding fragment thereof that binds a solid tumor antigen;
• and
• (ii) more than one viral T cell epitope that each elicit an existing immune response in the subject and that each bind to a HLA molecule on the surface of the cancer cell of the human subject and has a HLA matched to the subject,
• (iii) more than one peptide linker each comprising a peptide cleavage site cleavable by a tumor associated protease and
• wherein each linker can be selectively cleaved by a tumor associated protease to release each T cell epitope in the vicinity of, and outside of, the solid tumor cells,
• wherein each peptide linker is separately attached to the targeting moiety,
• wherein each linker attaches a single T cell epitope to the targeting moiety, and
• wherein the solid tumor is not a lymphoma.