Selective cyclocarbonylative coupling of 2-iodophenols with terminal alkynes catalyzed by bridged bis(NHC)Pd(II)Br2 catalysts
AssigneeKing Fahd University of Petroleum and Minerals
InventorsBassam El Ali, Waseem Mansour, Mohammed Fettouhi
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Abstract
Palladium catalysts, methods of synthesizing palladium-carbene catalysts, and methods of producing chromones and aurones using palladium-N-heterocyclic carbene (NHC) catalysts are provided. In some implementations, the palladium catalysts include a bridged palladium catalyst with distorted square planar geometry around the center palladium atom. The catalysts can be used in cyclocarbonylative Sonogashira cross-coupling reactions to produce chromones and aurones at a high yield. The selectivity of the catalysts can be adjusted by adjusting reaction conditions.
Claims4
A method of synthesizing chromones or aurones comprising reacting a 2-iodophenol and an aryl alkyne in the presence of a palladium catalyst under a carbon monoxide atmosphere, wherein the palladium catalyst comprises at least one of Formula (C1), Formula (C2), or Formula (C3), wherein
- Formula (C1) is
- Formula (C2) is
- Formula (C3) is
Dependencies are inferred from the claim text.