Functionalized heterocycles as antiviral agents

A compound represented by Formula (I):

• or a pharmaceutically acceptable salt thereof, wherein:
• R1 is hydrogen, optionally substituted —C1-C6 alkyl, or optionally substituted —C3-C6 cycloalkyl;
• R2 is hydrogen, halo, CN, optionally substituted C1-C6 alkyl, or optionally substituted C1-C6 alkoxy;
• R3 is selected from:
• 1) hydrogen;
• 2) halogen;
• 3) —NO2;
• 4) cyano;
• 5) optionally substituted —C1-C8 alkyl;
• 6) optionally substituted —C2-C8 alkenyl;
• 7) optionally substituted —C2-C8 alkynyl;
• 8) optionally substituted —C3-C8 cycloalkyl;
• 9) optionally substituted 3- to 8-membered heterocyclic;
• 10) optionally substituted aryl;
• 11) optionally substituted arylalkyl;
• 12) optionally substituted heteroaryl;
• 13) optionally substituted heteroarylalkyl;
• 14) —N(R11)(R12);
• 15) —OR11;
• 16) —SR11;
• and
• 17) —S(O)2R11;
• A is optionally substituted —C3-C8 cycloalkenyl;
• optionally substituted unsaturated 3- to 8-membered heterocycloalkyl;
• optionally substituted aryl;
• optionally substituted heteroaryl;
• Q is NR12, O, S, or SO2;
• R4 and R5 are each independently selected from hydrogen, halo, —N(R11)(R12), optionally substituted —C1-C6 alkyl, optionally substituted —C1-C6 alkoxy, optionally substituted —C3-C8 cycloalkyl;
• optionally substituted 3- to 8-membered heterocycloalkyl;
• optionally substituted aryl;
• and optionally substituted heteroaryl;
• alternatively, R4 and R5 are taken together with the carbon atom to which they are attached to form an optionally substituted 3-8 membered heterocyclic or carbocyclic ring containing 0, 1, 2, or 3 double bonds;
• R6 is hydrogen or optionally substituted methyl;
• W is —COOR11, —C(O)NHSO2R11, —C(O)NHSO2NR11R12, 5-tetrazolyl, or 1,2,4-oxadiazol-3-yl-5(4H)-one;
• and
• Each R11 and R12 is independently selected from hydrogen, optionally substituted —C1-C8 alkyl, optionally substituted —C2-C8 alkenyl, optionally substituted —C3-C8 cycloalkyl, optionally substituted 3- to 8-membered heterocycloalkyl, optionally substituted aryl, and optionally substituted heteroaryl, alternatively, R11 and R12 are taken together with the nitrogen atom to which they are attached to form an optionally substituted 3-8 membered heterocyclic containing 0, 1, 2, or 3 double bonds.