Crystal of tricyclic compound
AssigneeChia Tai Tianqing Pharmaceutical Group Co., Ltd.
InventorsShilan Liu, Dahai Wang, Guibai Liang, Honglin Wang, Guoping Hu, Jian Li, Shuhui Chen
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AssigneeChia Tai Tianqing Pharmaceutical Group Co., Ltd.
InventorsShilan Liu, Dahai Wang, Guibai Liang, Honglin Wang, Guoping Hu, Jian Li, Shuhui Chen
Estimating the term…
The present application relates to a crystal of a tricyclic compound, in particular to a crystal of (S)-8-(4,4-difluorocyclohexyl)-8H-thieno[3,4]pyrrolo[1,5-a]imidazole, a preparation method therefor, a crystal composition and a pharmaceutical composition thereof and the use thereof. The X-ray powder diffraction spectrum of the crystal of the compound of formula I in the present application, represented by a 2θ value, has a diffraction peak at about 11.49°, 15.05°, 20.14°, 21.53° or 21.79°. The crystal of the compound of formula I in the present application has excellent physical properties, high safety and metabolic stability, and has a good inhibitory effect on IDO and a high medicinal value.
A crystal of (S)-8-(4,4-difluorocyclohexyl)-8H-thieno[3,4]pyrrolo[1,5-a]imidazole represented by formula I,
Dependencies are inferred from the claim text.