Fruquintinib eutectic crystal, preparation method therefor, composition, and uses thereof
AssigneeHangzhou SoliPharma Co., Ltd.
InventorsXiaohong Sheng, Xiaoxia Sheng
Life of this patent
Estimating the term…
Abstract
Provided are a fruquintinib and a saccharin salt or eutectic crystal, a fruquintinib and a malonic acid eutectic crystal or a fruquintinib and a maleic eutectic crystal, a preparation method therefor, a pharmaceutical composition containing thereof, and uses thereof in preparing drugs for treating and/or preventing diseases related to abnormal angiogenesis, such as cancer, tumors, macular degeneration, chronic inflammation and the like.
Claims29
Compound A formed by fruquintinib and saccharin having the structure shown below:
A cocrystal of fruquintinib and malonic acid having the structure shown below:
A cocrystal of fruquintinib and maleic acid having the structure shown below:
Dependencies are inferred from the claim text.