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US 11,232,557 B2Granted
Image analysis
AssigneeEyeKor, LLC
InventorYijun Huang
Life of this patent
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Abstract
Provided herein is technology relating to analysis of images and particularly, but not exclusively, to methods and systems for determining the area and/or volume of a region of interest using optical coherence tomography data. Some embodiments provide for determining the area and/or volume of a lesion in retinal tissue using three-dimensional optical coherence tomography data and a two-dimensional optical coherence tomography fundus image.
Claims5
A system for determining the volume of a region of interest of a biological tissue, the system comprising:
- a) an OCT apparatus;
- and
- b) software to calculate an area and/or volume of the region of interest V by implementing the following steps in response to a user of the system:
- i) acquiring three-dimensional OCT data comprising at least a first segment and a second segment comprising a tissue abnormality;
- ii) acquiring two-dimensional image data comprising the tissue abnormality, wherein the tissue abnormality in the three-dimensional OCT data corresponds to the tissue abnormality in the two-dimensional data;
- iii) drawing a boundary around the tissue abnormality in the two-dimensional image data, the boundary enclosing an area A, wherein the two-dimensional image data and three-dimensional OCT data are registered via a computer processor so that the tissue abnormality is identified in the three-dimensional OCT data by the boundary drawn on the two-dimensional image and displayed on a computer screen;
- iv) calculating a volume v within the boundary and between the first segment and the second segment;
- v) calculating an average thickness t between the first segment and the second segment along the boundary;
- and
- vi) calculating the volume of the region of interest V=v−(t×A).
7 more elements
Dependencies are inferred from the claim text.