Particle separation and analysis

A system, comprising:

• an input channel to flow particles therethrough;
• a cell separation chamber in fluid communication with the input channel, the cell separation chamber including an array of columns spaced apart to facilitate separation of particles in a flow into at least two flow paths based on a size of the particles, wherein the size associated with a first flow path of the at least two flow paths corresponds to cell-sized particles;
• at least two output channels, each output channel coupled to the separation chamber to receive separated particles, wherein a first output channel is to receive the first flow path corresponding to the cell-sized particles;
• a cell lysing portion to mix a lysing agent with the cell-sized particles, the lysing agent to release biological material from cells;
• an integrated pump configured to facilitate flow through the separation chamber, the integrated pump being disposed entirely within an inside of at least one of the input channel or one of the at least two output channels;
• and
• a cell analysis portion to receive biological material from lysed cells, the cell analysis portion including at least one detection portion to identify a characteristic of the biological material.

A system, comprising:

• an input channel to flow particles therethrough;
• a cell separation chamber in fluid communication with the input channel, the cell separation chamber including an array of columns spaced apart to facilitate separation of particles in a flow into at least two flow paths based on a size of the particles, wherein the size associated with a first flow path of the at least two flow paths corresponds to cell-sized particles;
• at least two output channels, each output channel coupled to the separation chamber to receive separated particles, wherein a first output channel is to receive the first flow path corresponding to the cell-sized particles;
• a cell lysing portion to mix a lysing agent with the cell-sized particles, the lysing agent to release biological material from cells;
• an integrated pump configured to facilitate flow through the separation chamber, the integrated pump being disposed entirely within an inside of at least one of the input channel or one of the at least two output channels;
• and
• a biological material amplification portion to amplify biological material from lysed cells.