Methods and apparatus to deliver therapeutic, non-ultraviolet electromagnetic radiation versatilely via a catheter residing in a body cavity

A medical device assembly for insertion into a catheter having an elongate body with at least one internal lumen, a connecting end and a distal end, the connecting end having an external segment portion that remains outside a patient's body and the distal end being insertable into a cavity of the patient's body to define an indwelling portion of the catheter, the catheter facilitates delivery of a fluid to and/or retrieval of fluid from the patient's body, the medical device assembly comprising:

• an electromagnetic radiation (EMR) source for providing non-ultraviolet, therapeutic EMR having an intensity comprising a radiant exposure of at least 0.5 J/cm2 and up to 1.0 kJ/cm2 and power of at least 0.005 mW and up to 1 Watt, such intensity being sufficient to produce a therapeutic effect of at least one of inactivating one or more infectious agents and enhancing healthy cell growth;
• an EMR conduction system comprising an optical element, at least a portion of the optical element comprises a fiber optic for disposition within the at least one internal lumen of the catheter, the fiber optic comprises a fiber body having an exterior surface, a coupling end, a distal end, and a core, the fiber optic being conducive to the axial propagation of therapeutic EMR within the core relative to the external segment portion and the indwelling portion of the elongate catheter body, the fiber optic further comprises at least one radial emission portion disposed between the coupling end of the fiber body and the distal end of the fiber body, the radial emission portion allowing the emission of therapeutic EMR radially from the fiber body into the internal lumen of the catheter;
• at least one coupling to connect the EMR source to the EMR conduction system;
• and
• wherein at least one radial emission portion of the fiber body is disposed at a position such that the emission of the therapeutic EMR radially from the fiber body is directed to a location along the elongate catheter body for treatment region specific dosing of the therapeutic EMR.

A medical device assembly for insertion into a peritoneal cavity of a patient's body and for delivery of dialysis solution to and/or retrieval of waste dialysis solution from the patient's body, comprising:

• an electromagnetic radiation (EMR) source for providing non-ultraviolet, sterilizing EMR having an intensity comprising a radiant exposure of at least 0.5 J/cm2 and up to 1.0 kJ/cm2 and power of at least 0.005 mW and up to 1 Watt, such intensity being sufficient to produce a therapeutic effect of inactivating one or more infectious agents;
• a peritoneal dialysis catheter having an elongate catheter body with at least one internal lumen, a connecting end having an external segment portion that remains outside the patient's body and a distal end, the distal end being insertable into the peritoneal cavity of the patient's body to define an indwelling portion of the peritoneal dialysis catheter, wherein the elongate catheter body directs both the dialysis solution and the sterilizing EMR axially relative to the elongate catheter body, axial flow of the dialysis solution within the elongate catheter body facilitates delivery of dialysis into the patient's body and retrieval of waste dialysis solution from the patient's body;
• an EMR conduction system comprising an optical element, at least a portion of the optical element comprises a fiber optic for disposition within the at least one internal lumen of the elongate catheter body, the fiber optic comprises a fiber body having an exterior surface, a coupling end, a distal end, and a core, the fiber optic being conducive to the axial propagation of sterilizing EMR within the core relative to the external segment portion and the indwelling portion of the elongate catheter body, the fiber optic further comprises at least one radial emission portion disposed between the coupling end of the fiber body and the distal end of the fiber body, the radial emission portion allowing the emission of sterilizing EMR radially from the fiber body into the internal lumen of the elongate catheter body;
• at least one coupling to connect the EMR source to the EMR conduction system;
• and
• wherein at least one radial emission portion of the fiber body is disposed at a position such that the emission of the sterilizing EMR radially from the fiber body is directed to a location along the elongate catheter body for treatment region specific dosing of the therapeutic sterilizing EMR.