Optimized intrathecal drug delivery
AssigneeMedtronic, Inc.
InventorJeffrey Bodner
Life of this patent
Estimating the term…
Abstract
An intrathecal drug delivery system configured to monitor one or more physiological conditions of the patient to look for opportunities to time medicament delivery to coincide with patient activity inferring heightened cerebrospinal fluid oscillations, thereby improving dispersion of the medicament within the intrathecal space of the patient. The intrathecal drug delivery system includes an implantable medical pump, one or more physiological sensors, and an external programmer configured to program the implantable medical pump with a treatment protocol specifying at least one period of time during which a specified quantity of medicament is to be administered during which the implantable medical pump utilizes data from the one or more physiological sensors to time delivery of the medicament.
Claims15
An intrathecal drug delivery system configured to monitor one or more physiological conditions of a patient to look for opportunities to time medicament delivery to coincide with patient activity inferring heightened cerebrospinal fluid oscillations, thereby improving dispersion of the medicament within an intrathecal space of the patient, the intrathecal drug delivery system comprising:
- an implantable medical pump configured to deliver medicament within the intrathecal space of a patient;
- one or more physiological sensors configured to monitor at least one of a heart rate, respiratory rate, oxygen saturation, or perspiration rate of the patient;
- and
- an external programmer configured to program the implantable medical pump with a treatment protocol specifying at least one period of time during which a specified quantity of medicament is to be administered,
- wherein during the at least one period of time, the implantable medical pump is configured to administer the specified quantity of medicament upon at least one of the monitored heart rate, respiratory rate, oxygen saturation, or perspiration rate meeting or exceeding a patient specific active state threshold.
A method of timing intrathecal drug delivery to correspond with heightened cerebrospinal fluid oscillations, the method comprising:
- programming an implantable medical pump with a treatment protocol specifying at least one period of time during which a specified quantity of medicament is to be delivered into the intrathecal space of patient;
- monitoring one or more physiological conditions of the patient with one or more physiological sensors to determine at least one of a heart rate, respiratory rate, oxygen saturation, or perspiration rate;
- and
- timing the delivery of the medicament to coincide with at least one of the monitored heart rate, respiratory rate, oxygen saturation, or perspiration rate meeting or exceeding a patient specific active state threshold, thereby improving dispersion of the medicament within the intrathecal space of the patient.
Dependencies are inferred from the claim text.