Radiotherapy improvements

A method for inducing an abscopal response to radiotherapy in an individual, including:

• irradiating an individual having a plurality of tumors, and who has received idronoxil, with a cytotoxic dose of ionising radiation so that fewer than all of the plurality of tumors are irradiated, thereby resulting in the individual having irradiated and non-irradiated tumors,
• wherein at least one of the tumors is a primary tumor, and at least one of the tumors is a metastatic or secondary tumor of a primary tumor;
• wherein at least one of the primary, or metastatic or secondary tumors, is a prostate tumor;
• wherein idronoxil is administered to the individual about 12 to 24 hours before irradiating the individual and,
• wherein idronoxil is administered for 13 consecutive days, including 1 day before radiotherapy, on each day of radiotherapy, wherein the individual receives radiotherapy in 5 fractionated doses over 5 consecutive days, and on each day for 7 days following radiotherapy;
• wherein one or more non-irradiated tumors regress following administration of idronoxil and the irradiation of the individual, thereby inducing an abscopal response to radiotherapy in the individual.