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US 11,229,682 B2Granted
Methods of treatment for kidney disease
AssigneeWake Forest University Health Sciences
InventorJames K. Williams
Life of this patent
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Abstract
The present disclosure provides compositions and methods for treatment of a kidney disease with chemokine protein stromal cell-derived factor 1 (SDF-1), such as methods of treating a subject afflicted with or at risk of developing a kidney disease, comprising administering SDF-1 to a kidney of the subject in a treatment-effective amount.
Claims15
A method of treating a subject afflicted with a chronic kidney disease, comprising administering mammalian stromal cell-derived factor 1 alpha (SDF-1α) to a kidney of the subject in a treatment-effective amount,
- wherein said administering step is carried out by direct injection of the SDF-1α into said kidney, and
- wherein said administering of the treatment-effective amount of SDF-1α a results in decreased cellular disruption and/or decreased fibrosis of the kidney.
Dependencies are inferred from the claim text.