Methods for treating cholestasis
AssigneeMirum Pharmaceuticals, Inc.
InventorsThomas Jaecklin, Alejandro Dorenbaum
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Abstract
Provided herein are methods for treating cholestasis in a subject having a liver disease. The method includes administering to the subject an Apical Sodium-dependent Bile Acid Transporter (ASBTI). More specifically, the present invention relates to methods for treating cholestasis in a subject where the method includes administering an ASBTI to a subject at a dose of at least 10 μg/kg/day.
Claims13
A method for treating Alagille Syndrome (ALGS) in a pediatric subject in need of such treatment comprising administering to the subject
- (maralixibat chloride), wherein maralixibat chloride is administered in an amount of from about 400 μg/kg/day to about 800 μg/kg/day.
A method for treating Alagille Syndrome (ALGS) in a pediatric subject in need of such treatment comprising administering to the subject
- (maralixibat chloride), wherein maralixibat chloride is administered in an amount of about 400 μg/kg/day.
A method for treating Alagille Syndrome (ALGS) in a pediatric subject in need of such treatment comprising administering to the subject
- (maralixibat chloride), wherein maralixibat chloride is administered in an amount of about 800 μg/kg/day.
Dependencies are inferred from the claim text.