Method of treating fibrosis
AssigneeBCN Biosciences L.L.C.
InventorAndrew J. Norris
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Abstract
The present disclosure is directed to method of treatment for treating or ameliorating various conditions pertaining such as bone marrow recovery (or blood cell production), fibrosis, inflammatory diseases, inhibition of cancer cell growth, propagation or malignancy, thrombocytopenia, wound healing, and conditions related to stem cells by the administration of BCN057, 512, or an analog thereof.
Claims7
A method of treating fibrosis in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of BCN512 according to the following structure:
- wherein the fibrosis is not induced by ionizing radiation.
A method of treating fibrosis in a subject in need thereof, comprising administering a therapeutically effective amount of an analog of BCN512 to the subject, wherein the analog is selected from the group consisting of:
- wherein:
- Y1 and Y2 taken together with X form:
- and wherein:
- X is N;
- G is N;
- Z is absent or selected from substituted or unsubstituted alkyl, heteroalkyl, alkenyl, or alkynyl;
- R4 is absent or selected from substituted or unsubstituted aryl;
- and
- R5 and R6 are each independently absent or lower alkyl wherein the fibrosis is not induced by ionizing radiation.
Dependencies are inferred from the claim text.