Synergistic nutritional compositions for treating seizures and chronic inflammatory diseases
AssigneeCelagenex Research (India) Pvt. Ltd.
InventorsRajaram Samant, Rajendra Prasad Tongra
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Abstract
The invention disclosed herein relates to novel synergistic nutritional compositions for treating seizures and chronic inflammatory diseases. Particularly, the invention relates to potent and stable synergistic nutritional composition comprising combination of therapeutically active non-competitive amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPAR) antagonists and nuclear factor erythroid 2-related factor 2 (NRF2) activators, present in weight ratio of 1:0.001 to 1:0.5, along with pharmaceutically acceptable excipients. Further, the present synergistic nutritional composition is useful for treating conditions associated with seizure, fibrosis and diabetes.
Claims6
A novel, stable, synergistic nutritional composition comprising:
- a therapeutic exogenous combination of an effective amount of tridecanoin and white crystalline L-ergothioneine, present in a weight ratio of 1:0.001 to 1:0.5 along with pharmaceutically acceptable excipients.
A stable, orally active anti-seizure nutritional composition comprising:
- a synergistic combination of a therapeutically effective amount of tridecanoin and L-ergothioneine, wherein the tridecanoin and the L-ergothioneine are present in a weight ratio of 1:0.002 to 1:0.2 along with pharmaceutically acceptable excipients.
Dependencies are inferred from the claim text.